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Sotalol

Betapace

Test Codes

EPIC: LAB6333, Beaker: XSOTL, Mayo: FSOTA

Department

Send Outs

Specimen Collection Criteria

Collect (preferred specimen): One plain Red-top tube.
Also acceptable: One Dark Green-top sodium heparin tube.

Do not use Serum Separator or Plasma Separator Tubes.

Physician Office/Draw Specimen Preparation

Centrifuge to separate serum or plasma from cells within two hours of collection. Transfer serum or plasma to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Preparation for Courier Transport

Transport: 2.0 mL serum or plasma, refrigerated (2-8°C or 36-46°F). (Minimum: 0.3 mL)

Rejection Criteria

• Serum Separator (SST) or Plasma Separator (PST) tubes.
• Specimens not collected and processed as indicated.

In-Lab Processing

Centrifuge to separate serum or plasma from cells within two hours of collection. Transfer serum or plasma to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Transport: 2.0 mL serum or plasma, refrigerated (2-8°C or 36-46°F). (Minimum: 0.3 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 72 hours
Refrigerated (2-8°C or 36-46°F): 14 days
Frozen (-20°C/-4°F or below): 180 days

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to Mayo Clinic Laboratories in Rochester, MN. Forwarded to Medtox Laboratories.

Performed

Monday – Sunday
Results available in 6-10 days.

Reference Range

By report.

Test Methodology

High Performance Liquid Chromatography with Fluorescence Detection (HPLC-FL)

Interpretation

By report.

Clinical Utility

This assay aids in the therapeutic monitoring of sotalol (Betapace). Sotalol is an antiarrhythmic drug with Class II (beta-adrenoreceptor blocking) and Class III (cardiac action potential duration prolongation) properties. Sotalol (Betapace) is indicated for the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, that is judged to be life-threatening.

CPT Codes

80375

Contacts

Last Updated

9/25/2023