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Serotonin Release Assay

SRA

Test Codes

EPIC: LAB6506, Beaker: XSRA, ARUP: 2005631

Department

Send Outs

Instructions

This test is now ordered automatically on patients with a Heparin Platelet Factor 4 Antibody OD of 0.4 to 1.999. The SRA should only be ordered directly when there is a very strong clinical suspicion of heparin induced thrombocytopenia. In such cases, the ordering physician will need approval from a pathologist or pathology resident. Contact the Laboratory at 800-551-0488 with any questions.

Specimen Collection Criteria

Collect: Two Gold-top SST tubes.

Send specimens to the Laboratory immediately after collection for processing. 

Physician Office/Draw Specimen Preparation

Let specimens clot 30-60 minutes then centrifuge to separate serum from cells. Transfer serum to plastic transport tubes and immediately freeze (-20°C/-4°F or below).

Preparation for Courier Transport

Transport: 5.0 mL serum, frozen (-20°C/-4°F or below). (Minimum: 1.0 mL)

Rejection Criteria

Specimens not collected and processed as indicated.

In-Lab Processing

Let specimens clot 30-60 minutes then centrifuge to separate serum from cells. Transfer serum to plastic transport tubes and freeze (-20°C/-4°F or below) immediately.

Transport: 5.0 mL serum, frozen (-20°C/-4°F or below). (Minimum: 1.0 mL)

Refrigerated (2-8°C or 36-46°F) acceptable if received within 7 days.

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): Unacceptable
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): Indefinitely

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to ARUP Laboratory in Salt Lake City, UT

Performed

Monday – Saturday.
Results available in 3-5 days.

Reference Range

By report.

Test Methodology

Qualitative Serotonin Release Assay.

CPT Codes

86022

Contacts

Last Updated

9/25/2023