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Inhibin B

Test Codes

Mayo: INHB, EPIC: LAB6286, Beaker: XINHB

Specimen Collection Criteria

Collect (preferred specimen): One Gold-top SST tube.
Also acceptable: One plain Red-top tube.

Physician Office/Draw Specimen Preparation

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells. Transport serum to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Preparation for Courier Transport

Transport: 0.5 mL serum, refrigerated (2-8°C or 36-46°F). (Minimum: 0.2 mL)

Rejection Criteria

• Hemolyzed specimens.
• Specimens not collected and processed as indicated.

In-Lab Processing

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells. Transport serum to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Transport: 0.5 mL serum, refrigerated (2-8°C or 36-46°F). (Minimum: 0.2 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): Unacceptable
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): 90 days

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to Mayo Clinic Laboratories in Rochester, MN.

Performed

Monday, Wednesday, Friday.
Results available in 2-7 days.

Reference Range

By report.

Test Methodology

Quantitative Enzyme-Linked Immunosorbent Assay.

Interpretation

Indications for testing:

Women aged 35 years or greater, women of any age experiencing unexplained infertility who have a poor response to ovulation induction, women presenting for other tests of ovarian reserve including day 3 FSH and clomiphene challenge test, and women experiencing recurrent pregnancy losses should be tested for day 3 Inhibin B concentrations.

Clinical Utility

This test is for evaluating ovarian function. Inhibin B serum concentration provides a measure of ovarian reserve. Ovarian reserve describes the ovary's capacity to respond to gonadotropin stimulation by producing a sufficient number of good quality eggs capable of generating normal embryos. Inhibin B serum concentrations drawn on cycle day 3 have been shown to predict response of ovaries to gonadotropin stimulation in invitro fertilization (IVF) cycles.

CPT Codes

83520

Contacts

Last Updated

11/13/2020