Lab Test

Heavy Metals Screen, 24-Hour Urine

Test Codes

Mayo: HMU24, EPIC: LAB6048, Beaker: XHMU

Department

Send Outs

Instructions

  • High concentrations of gadolinium and iodine are known to interfere with most metals tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.
  • Patient should not eat seafood for a 48-hour period prior to start of, or during, collection.

Specimen Collection Criteria

Collect (preferred specimen): 24 hour urine sample with acceptable preservative.
Keep 24 hour urine specimen iced or refrigerated during collection.

  • Include start and end dates and times for the collection period on the specimen container.
Urine Preservative Options
No Preservative
6N Hydrochloric Acid
(30 ml)
Boric Acid (10g)
Sodium Carbonate
50% Acetic Acid
Unacceptable
Acceptable
Unacceptable
Unacceptable
Acceptable

Physician Office/Draw Specimen Preparation

Maintain specimens refrigerated (2-8°C or 36-46°F) prior to transport.

Preparation for Courier Transport

Transport: Entire 24-hour urine collection, refrigerated (2-8°C or 36-46°F).

Rejection Criteria

Specimens not collected and processed as indicated.

In-Lab Processing

Measure total volume of 24-hour urine specimen. Record total volume and collection start and end dates and times in the LIS system. Aliquot 10.0 mL from the well-mixed preserved 24-hour urine collection (Minimum: 3.0 mL).

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): unacceptable
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): 7 days

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to Mayo Clinic Laboratories in Rochester, MN.

Performed

Monday – Saturday.
Results available in 2-5 days.

Reference Range

By report.

Test Methodology

Quantitative Inductively Coupled Plasma / Mass Spectrometry.

Interpretation

By report.

Clinical Utility

Detecting arsenic, cadmium, mercury, and lead exposure and toxicity using 24-hour urine specimens

CPT Codes

82175, 82300, 83655, 83825.
LOINC:  Arsenic: Inorganic 12481-8, Organic 53778-7, Total 5586-3; Mercury 6693-6

Contacts

Last Updated

1/18/2022

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