Lab Test

Chronic Urticaria Index

CU Index, Anti-FceR™, CD203

Test Codes

ARUP: 2005413, EPIC: LAB6520, Beaker: XCUIN

Department

Send Outs

Instructions

  • Patients taking calcineurin inhibitors should stop their medications 72 hours prior to draw.
  • Patients taking Prednisone should stop their medication 2 weeks prior to draw.

Specimen Collection Criteria

Collect (preferred specimen): One plain Red-top tube.

Physician Office/Draw Specimen Preparation

CRITICAL FROZEN. Separate serum from cells within 2 hours of collection. Transfer 1 mL serum to a plastic transfer tube and freeze immediately. (Minimum: 0.5 mL)

Preparation for Courier Transport

Transport: 1 mL serum, frozen (-20°C/-4°F or below). (Minimum: 0.5 mL)

Rejection Criteria

Specimens not collected and processed as indicated.

Specimens other than serum.

In-Lab Processing

CRITICAL FROZEN. Separate serum from cells within 2 hours of collection. Transfer 1 mL serum to a plastic transfer tube and freeze immediately. (Minimum: 0.5 mL)

Transport: 1 mL serum, frozen (-20°C/-4°F or below). (Minimum: 0.5 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): unacceptable
Refrigerated (2-8°C or 36-46°F): unacceptable
Frozen (-20°C/-4°F or below): 365 days (avoid repeat freeze/thaw cycles)

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to ARUP Laboratories, Salt Lake City, UT.

Performed

Monday – Friday.
Results available in 3-7 days

Reference Range

10 Units or less.

Test Methodology

Semi-Quantitative Ex Vivo Challenge/Cell Culture/Quantitative Enzyme-Linked Immunosorbent Assay.

Clinical Utility

Chronic Idiopathic Urticaria (CIU) is a form of hives that lasts for more than six weeks with no obvious cause. 30-50% of CU is believed to be autoimmune. Two antibodies have been identified. Most commonly, auto-antibodies against high-affinity IgE receptor, FceR1, and also auto-antibodies against IgE are present in patients with Chronic Idiopathic Urticaria.

CPT Codes

86352
LOINC:  63369-3

Contacts

Last Updated

8/31/2021

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