Tricyclic Antidepressant (TCA) Screen, Urine
Elavil, Aventyl, Pamelor, Tofranil, Norpramin, Sinequan, Amitriptyline, Nortriptyline, Imipramine, Desipramine, Doxepin
EPIC: LAB7095, SOFT: TCASC
Specimen Collection Criteria
Collect: 30 mL random urine in a sterile collection container.
Physician Office/Draw Specimen Preparation
Maintain specimen refrigerated (2-8 oC or 36-46 oF) prior to transport.
Preparation for Courier Transport
Transport: Urine in a sterile collection container, refrigerated (2-8°C or 36-46°F). (Min: 15 mL urine)
Specimens not collected and processed as indicated.
Deliver the urine sample in its original container immediately to the appropriate testing station.
Specimen Stability for Testing:
Room Temperature (20-26°C or 68-78.8°F): 2 hours
Refrigerated (2-8°C or 36-46°F): 8 hours
Frozen (-20°C/-4°F or below): 3 months
Specimen Storage in Department Prior to Disposal:
Frozen (-20°C/-4°F or below): 2 months
Royal Oak Toxicology Laboratory
Sunday - Saturday, 24 hours a day.
STAT results available within 4 hours of receipt in the Laboratory.
Routine results available within 24 hours.
Gas Liquid Chromatography/Mass Spectrometry. (GC/MS).
This test was developed and its performance characteristics determined by Beaumont Health. It has not been cleared or approved by the FDA. The Laboratory is regulated under CLIA as qualified to perform high-complexity testing. This test is used for clinical purposes and should not be regarded as investigational or for research.
This assay screens urine for the presence of the following drugs: Amitriptyline, Nortriptyline, Imipramine, Desipramine, Doxepin, Clomipramine, Trimipramine and metabolites.
Serum quantitation of these drugs is available as a separate request.
This assay is designed primarily for the detection of toxic concentrations of tricyclic antidepressants.
LOINC: 19312-8, Amitriptyline 3333-2
Toxicology Laboratory – RO
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