Suboxone, Urine

Buprenex, Butrans, Subutex, Buprenorphine, Naloxone

Test Codes

EPIC: LAB1231349, Beaker: XUSUB, Warde: UCSUB

Department

Send Outs

Specimen Collection Criteria

Collect: Random urine in a screw-capped container (preferred) or other sterile collection container. (Minimum: 3.0 mL)

Physician Office/Draw Specimen Preparation

Maintain specimen refrigerated (2-8°C or 36-46°F) prior to transport.

Preparation for Courier Transport

Transport: Random urine, refrigerated at (2-8°C or 36-46°F). (Minimum: 3.0 mL)

Rejection Criteria

Specimens not collected and processed as indicated.

In-Lab Processing

Maintain specimen refrigerated (2-8°C or 36-46°F) prior to transport.

Transport: Random urine, refrigerated (2-8°C or 36-46°F). (Minimum: 3.0 mL) 

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 48 hours
Refrigerated (2-8°C or 36-46°F): 14 days
Frozen (-20°C/-4°F or below): 30 days

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to Warde Medical Laboratory, Ann Arbor, MI.

Performed

Monday – Friday.
Results available in 1-3 days. 

Reference Range

Positive Cutoff
Buprenorphine: 5.0 ng/mL.
Naloxone: 5.0 ng/mL.
Norbuprenorphine: 5.0 ng/mL.

Test Methodology

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Interpretation

Drug covered by this test include Buprenorphine, Naloxone, and Norbuprenorphine.

CPT Codes

80348, 80362.

Contacts

Last Updated

2/9/2026