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Streptomycin Serum Level, HPLC

Test Codes

EPIC: LAB6444, Beaker: XSTMY, National Jewish: PKSM

Department

Send Outs

Specimen Collection Criteria

Collect (preferred specimen): One plain Red-top tube.
Also acceptable: One Green-top Sodium Heparin tube.

Do not use Serum Separator Tubes.

Physician Office/Draw Specimen Preparation

Centrifuge to separate serum or plasma from cells. Transfer serum or plasma to a plastic transport tube and freeze (-20°C/-4°F or below) immediately.

Preparation for Courier Transport

Transport: 2.0 mL serum, frozen (-20°C/-4°F or below). (Minimum: 0.5 mL)

Rejection Criteria

• Serum Separator (SST) tubes.
• Grossly hemolyzed specimens.
• Specimen not collected and processed as indicated.

In-Lab Processing

Centrifuge to separate serum or plasma from cells. Transfer serum or plasma to a plastic transport tube and freeze (-20°C/-4°F or below) immediately.

Transport: 2.0 mL serum, frozen (-20°C/-4°F or below). (Minimum: 0.5 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 24 hours
Refrigerated (2-8°C or 36-46°F): 24 hours
Frozen (-20°C/-4°F or below): 30 days

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to National Jewish Health, Denver, CO.

Performed

Monday – Friday.
Results available within 10 days.

Reference Range

By report.

Test Methodology

High Performance Liquid Chromatography (HPLC).

Interpretation

By report.

Clinical Utility

Streptomycin is a systemic aminoglycoside. It is used primarily as an antitubercular and is active against Mycobacterium tuberculosis and M. bovis. It is also considered the drug of choice for the treatment of infections caused by Francisella tularensis and Yersinia pestis, and is often used to treat Brucella infections. Because many other gram-negative bacilli are resistant, streptomycin is rarely used to treat those organisms.

CPT Codes

80299
LOINC: 460-6

Contacts

Last Updated

7/3/2023