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Respiratory Pathogens by Film Array

RVP, Adenovirus, Coronavirus, SARS-CoV-2, COVID-19, Human Metapneumovirus (hMPV), Influenza A, Influenza B, Pandemic Influenza H1N1 2009, Parainfluenza, Respiratory Syncytial Virus (RSV), Rhinovirus / Enterovirus, Mycoplasma pneumoniae, Respiratory Pathogen Panel by PCR, Respiratory Pathogens by Film Array, IRP

Test Codes

EPIC: LAB3359

Department

Molecular Pathology

Instructions

• The Respiratory Pathogen Panel by PCR contains 23 viral and bacterial targets: Influenza A (including subtypes H1, H3, and H1N1), Influenza B, RSV (A/B), Metapneumovirus, Rhinovirus/Enterovirus, Adenovirus, Parainfluenza virus 1-4, Coronavirus (SARS-CoV-2, 229E, NL63, HKU1, and OC43), Human Bocavirus, Chlamydophila pneumoniae, Mycoplasma pneumoniae and legionella pneumophila.
• RVP, Flu, RSV, and Covid swabbing should be performed at the physician office.
• Please see instructions for Nasopharyngeal (NP) Swab Collection. 

Specimen Collection Criteria

• Nasopharyngeal (NP) Swab: Place in viral transport medium (i.e., UVT, UTM).
  • During collection, please remember to leave the NP swab in the patient's nasopharynx for 30 seconds and to gently rotate the swab to obtain an adequate specimen. For more information, please refer to the Specimen Collection Manual for NP Swab Collection.

Physician Office/Draw Specimen Preparation

As of 08/28/2024, this test is no longer orderable in the outpatient setting.

Preparation for Courier Transport

Transport: All specimen types refrigerated (2-8°C or 36-46°F) or on wet ice.

Rejection Criteria

• Dry swabs.
• Plasma or serum.
• Samples collected in bacterial transport media such as ESwab.
• Contaminated media (e.g. yellow in color or contain black particles).

In-Lab Processing

Maintain specimens refrigerated (2-8°C or 36-46°F) until testing.

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 2 hours
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): Unacceptable

Specimen Storage in Department Prior to Disposal:

Refrigerated (2-8°C or 36-46°F): 7 days

Laboratory

Royal Oak Molecular Pathology Laboratory

Performed

Sunday – Saturday.
Results available within 24-48 hours. 

Reference Range

Not Detected for all targets.

Test Methodology

Luminex NxTAG^® Respiratory Pathogen Panel v2 (NxTAG^® Respiratory Pathogen Panel v2 Package Insert, Luminex Molecular Diagnostics, Inc. Toronto, ON, Canada)

Multiplex Nucleic Acid Amplification. This test has been approved by the FDA for nasopharyngeal swab specimens.

Interpretation

By report.

Clinical Utility

The panel detects 23 commonly encountered respiratory pathogens:

• Adenovirus
• SARS-CoV-2 (COVID-19)
• Seasonal Coronavirus Types OC43, HKU1, NL63, 229E
• Human Metapneumovirus
• Influenza A and B with Influenza A subtyping [seasonal A H1, seasonal A H3, A H1N1 (2009)]
• Parainfluenza Types 1-4
• Respiratory Syncytial Virus Types A and B
• Rhinovirus/Enterovirus
• Human Bocavirus
• Chlamydophilia pneumoniae
• Mycoplasma pneumoniae
• Legionella pneumophila

CPT Codes

87633
LOINC: 55465-9, Influenza B 40982-1, Respiratory Syncytial Virus Type A & B 40988-8, Human Metapneumovirus 38917-1, Rhinovirus / Enterovirus 40991-2, Adenovirus 21055-9, Parainfluenza Type 1: 29908-1, Parainfluenza Type 2: 29909-9, Parainfluenza Type 3: 29910-7, Parainfluenza Type 4: 41010-0, SARS-CoV-2 (COVID-19): 96094-8, Coronavirus 229E: 41009-2, Coronavirus NL63: 62423-9, Coronavirus HKU1: 41005-0, Coronavirus OC43: 41003-5, Human Bocavirus 88613-5, Influenza A H1N1 (2009) 55465-9, Mycoplasma pneumoniae: 87581, Chlamydophila pneumoniae: 87486, Legionella pneumophila: 87541

Contacts

Last Updated

8/29/2025