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Pyruvic Acid CSF

Test Codes

EPIC: LAB6764, Beaker: XPACS, Mayo: PYRC

Department

Send Outs

Specimen Collection Criteria

Collect (preferred specimen):  0.6 mL CSF in a sterile container.

Rejection Criteria

Specimens not collected and processed as indicated.

In-Lab Processing

Transport: 0.6 mL CSF in sterile collection container, refrigerated (2-8°C or 36-46°F). (Minimum: 0.3 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 7 days
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): 7 days

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to Mayo Clinic Laboratories in Rochester, MN.

Performed

Monday, Thursday.
Results available in 7-9 days.

Reference Range

By report.

Test Methodology

Spectrophotometry (SP).

Clinical Utility

• Pyruvic and lactic acid levels are widely used as measures of "oxygen-debt." These measurements are helpful in that they provide an index of the severity of circulatory failure.
• Pyruvic acid is also helpful in evaluating patients with inborn errors of metabolism leading to increased serum lactate levels. A lactate to pyruvate ratio less than 25 suggests defective gluconeogenesis, whereas a ratio 35 or greater is consistent with hypoxia. An elevated CSF pyruvate has been reported in patients with Alzheimer's disease.

CPT Codes

84210
LOINC:  14122-6, 2905-8

Contacts

Last Updated

12/16/2022