Plasminogen Activator Inhibitor (PAI-1) AG

Plasminogen Activator Inhibitor-1 Antigen, Plasma

Test Codes

EPIC: LAB1232098, Beaker: Plasminogen, Quest: 36555

Department

Send Outs

Specimen Collection Criteria

Collect: One Light Blue-top Sodium Citrate tube.

Critical frozen. Send specimen for processing immediately after collection.

Physician Office/Draw Specimen Preparation

Centrifuge to separate p plasma from cells. Transfer serum to plastic transport tube and freeze (-20°C/-4°F or below) prior to transport.

Preparation for Courier Transport

Transport: Whole blood at room temperature (20-26°C or 68-78.8°F), or 1.0 mL platelet poor plasma (PPP) obtained through the process listed above, frozen (-20°C/-4°F or below). (Minimum: 0.5 mL PPP)

Rejection Criteria

• Non-citrated plasma.
• Non-frozen specimens.
• Specimens not collected and processed as indicated.

In-Lab Processing

Centrifuge to separate plasma from cells. Transfer serum to plastic transport tube and freeze (-20°C/-4°F or below) prior to transport.

Transport: 1.0 mL platelet poor plasma (PPP) obtained through the process listed above, frozen (-20°C/-4°F or below). (Minimum: 0.5 mL PPP)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): Unacceptable
Refrigerated (2-8°C or 36-46°F): 2 hours
Frozen (-20°C/-4°F or below): 30 days

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to Quest Diagnostics, Wood Dale, IL.

Performed

Tuesday.
Results are available in 3-10 days.

Reference Range

4-43 ng/mL

Test Methodology

Enzyme Immunoassay (EIA)

Interpretation

By report.

Clinical Utility

Plasminogen Activator Inhibitor (PAI-1) Ag – Increased activity is associated with increased risk of arterial thrombosis, such as with unexplained premature myocardial infarction. As an acute phase reactant, the activity is increased after an acute event. Studies suggest PAI-1 may be a prognostic marker in early stage breast cancer.

CPT Codes

85415

Contacts

Last Updated

12/19/2025