Parvovirus B19 Antibodies (IgG, IgM)

Erythema infectiosum (EI) Antibodies, Fifth Disease Antibodies, Hungarian Measles Antibodies, Human Parvovirus Antibody, Human Parvovirus B19 IgG, IgM, Fifth's Disease

Test Codes

EPIC: LAB1232050, Beaker: Parvovirus, Quest: 8946

Department

Send Outs

Specimen Collection Criteria

Collect: One gold-top SST Tube (SST).

Physician Office/Draw Specimen Preparation

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells. Transfer serum to plastic transport tube and maintain at room temperature (20-26°C or 68-78.8°F) prior to transport.

Preparation for Courier Transport

Transport: 2.0 mL serum, room temperature (20-26°C or 68-78.8°F). (Minimum: 1.0 mL)

Rejection Criteria

• Plasma specimens. 
• Severely hemolyzed, lipemic or icteric specimens. 
• Specimens not collected and processed as indicated. 

In-Lab Processing

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells. Transfer serum to plastic transport tube and maintain at room temperature (20-26°C or 68-78.8°F).

Transport: 2.0 mL serum, room temperature (20-26°C or 68-78.8°F). (Minimum: 1.0 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 4 days
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): 30 days

Laboratory

Sent to Quest Diagnostics, Wood Dale, IL.

Performed

Information not available.

Reference Range

Parvovirus B19 Ab (IgG)        <0.9
Parvovirus B19 Ab (IgM)        <0.9

Interpretive Criteria
<0.9             Negative
0.9-1.1         Equivocal
>1.1              Positive

Test Methodology

Immunoassay (IA)

Clinical Utility

Parvovirus B19 is also known as Fifth Disease. It primarily affects children and causes a rash on the face, trunk, and limbs. Joint pain and swelling is more common in adults. Although one-fifth of those affected have only mild disease, patients with sickle cell anemia or similar types of chronic anemia can suffer from acute anemia. Infection during pregnancy can lead to complications.

Reference

1. Wiedbrauk D, Johnston SLG. Manual of Clinical Virology, Raven Press, New York, NY, 1993.

CPT Codes

86747x2.

Contacts

Last Updated

12/17/2025