NMDA Receptor (NR1-Subunit) Autoantibody Test

NMDA, Anti- GluN1, Glutamate Receptor Antibodies, Anti- NR1, Glutamate Receptor Antibodies, N-Methyl-D-Aspartate Receptor Antibody, Serum, NMDA Receptor Antibody, Serum

Test Codes

EPIC: LAB12321341, Beaker: NMDAS, Quest: 92394

Department

Send Outs

Specimen Collection Criteria

Collect: One Gold-top SST tube.

Also Acceptable: One plain Red-top tube.

Physician Office/Draw Specimen Preparation

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells within two hours of collection. Transfer serum to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Preparation for Courier Transport

Transport: 2.0 mL serum, refrigerated (2-8°C or 36-46°F). (Minimum: 0.5 mL)

Rejection Criteria

• Turbid.
• Bacterial Contamination.
• Specimens not collected and processed as indicated.

In-Lab Processing

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells within two hours of collection. Transfer serum to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Transport: 2.0 mL serum, refrigerated at (2-8°C or 36-46°F). (Minimum: 0.5 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 72 hours
Refrigerated (2-8°C or 36-46°F): 28 days
Frozen (-20°C/-4°F or below): 28 days

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to Quest Diagnostics, Wood Dale, IL.

Performed

Sunday – Thursday.
Results available in 5-7 days.

Reference Range

Technical Results:

Negative

Test Methodology

Immunofluorescence Assay (IFA)

Clinical Utility

NMDA Receptor (NR1-subunit) Autoantibody Test - Anti-NMDA receptor (NR1-subunit) antibody is found in patients with encephalitis, acute psychiatric disturbances, seizures, memory deficits, and hypoventilation.

CPT Codes

86255

Contacts

Last Updated

12/17/2025