Neisseria meningitidis IgG Vaccine MAID

Serogroups A, C, W-135, & Y, Neisseria meningitidis Tetravalent Antibodies, IgG, Meningococcal Serology, Meningitis Vaccine, Neisseria meningitidis Antibody

Test Codes

EPIC: LAB1231993, Beaker: NMENIGIGG, Quest: 15903

Department

Send Outs

Specimen Collection Criteria

Collect (preferred specimen): One Gold-top SST tube.

Also acceptable: One plain Red-top tube.

Physician Office/Draw Specimen Preparation

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells. Transfer serum to plastic transport tube and maintain at room temperature (20-26°C or 68-78.8°F) prior to transport.

Preparation for Courier Transport

Transport: 0.5 mL serum, room temperature (20-26°C or 68-78.8°F). (Minimum: 0.3 mL)

Rejection Criteria

Specimens not collected and processed as indicated.

In-Lab Processing

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells. Transfer serum to plastic transport tube and maintain at room temperature (20-26°C or 68-78.8°F) prior to transport.

Transport: 0.5 mL serum, room temperature (20-26°C or 68-78.8°F). (Minimum: 0.3 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 7 days
Refrigerated (2-8°C or 36-46°F): 14 days
Frozen (-20°C/-4°F or below): 30 days

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to Quest Diagnostics, Wood Dale, IL.

Performed

Tuesday.
Results available in 2-8 days.

Reference Range

Serogroup A:               <4.0 ug/mL
Serogroup C:               <5.0 ug/mL
Serogroup Y:               <4.0 ug/mL
Serogroup W-135:      <3.0 ug/mL

Test Methodology

Multi-Analyte Immunodetection (MAID)

Clinical Utility

Neisseria meningitidis, IgG, Vaccine Response, MAID - This assay measures serum IgG antibodies recognizing polysaccharide antigens from the four Neisseria meningitidis serogroups included in the licensed meningococcal vaccine. The meningococcal vaccine response is best evaluated by testing pre-vaccination and post-vaccination samples in parallel. A two-fold or greater increase for at least two serogroups is expected when comparing post-vaccination to pre-vaccination results. N. Meningitidis IgG levels peak approximately one month post-vaccination but decline markedly by two years.

CPT Codes

86317 (x4)

Contacts

Last Updated

11/25/2025