Methylmalonic Acid, Urine with Creatinine

Methylmalonic Acid, Random Urine

Test Codes

EPIC: LAB1232132, Beaker: MMA RanUR, Quest: 91032

Department

Send Outs

Specimen Collection Criteria

Collect: Random urine specimen in a screw-capped container (preferred) or other sterile collection cup. (Minimum: 0.6 mL)

Physician Office/Draw Specimen Preparation

Refrigerate (2-8°C or 36-46) urine specimens prior to transport.

Preparation for Courier Transport

Transport: 1.7 mL serum, refrigerated at (2-8°C or 36-46). (Minimum: 0.6 mL)

Rejection Criteria

• Received room temperature.
• Acidified urine.
• Specimens not collected and processed as indicated.

In-Lab Processing

Refrigerate (2-8°C or 36-46) urine specimens.

Transport: 1.7 mL serum, refrigerated (2-8°C or 36-46). (Minimum: 0.6 mL)

Storage

Specimen Stability for Testing:

Room temperature (20-26°C or 68-78.8°F): 4 days
Refrigerated (2-8°C or 36-46°F): 12 days
Frozen (-20°C/-4°F or below): 30 days

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to Quest Diagnostics, Wood Dale, IL.

Performed

Tuesday, Friday.
Results available in 4-8 days.

Reference Range

Methylmalonic Acid, Urine

0.3-2.2 mmol/mol creat

Creatinine, Random Urine

0-6 Months	0.18-2.48 mmol/L
7-11 Months	0.18-2.74 mmol/L
1-2 Years	0.18-9.72 mmol/L
3-8 Years	0.18-11.49 mmol/L
9-12 Years	0.18-14.14 mmol/L
>12 Years	1.77-23.31 mmol/L

Test Methodology

Chromatography / Mass Spectrometry

Interpretation

By report.

Clinical Utility

Methylmalonic Acid (MMA) is useful to diagnose and monitor Vitamin B₁₂ (cobalamin) deficiency, and to diagnose and monitor patients with methylmalonic acidemia.

CPT Codes

83921, 82570

Contacts

Last Updated

12/19/2025