Lab Test

Methotrexate Post Glucarpidase, Serum

Test Codes

EPIC: LAB7109, Beaker: XMETS, MAYO: MTXSG

Department

Send Outs

Specimen Collection Criteria

Collect: One Gold-top Serum Separator (SST) tube

Also acceptable: One plain Red-top tube.

  • Must protect from light.

Physician Office/Draw Specimen Preparation

Centrifuge to separate serum from cells. Transfer serum to light protected plastic transport tube and refrigerate (2-8°C or 36-46°F).

Preparation for Courier Transport

Transport: 1.0 mL serum, refrigerated (2-8°C or 36-46°F). (Minimum: 0.2 mL)

Rejection Criteria

  • Samples exposed to light >24 hours
  • Specimens not collected and processed as indicated.

In-Lab Processing

Centrifuge to separate serum from cells. Transfer serum to light protected plastic transport tube and refrigerate (2-8°C or 36-46°F).

Transport: 1.0 mL serum, refrigerated (2-8°C or 36-46°F). (Minimum: 0.2 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 7 days
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): 14 days

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to Mayo Medical Laboratories, Rochester, MN.

Performed

Monday – Sunday.
Results available in 2 days.

Reference Range

By report.

Test Methodology

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS).

Interpretation

By report.

Clinical Utility

Monitoring methotrexate concentrations postglucarpidase therapy.

CPT Codes

80299

Contacts

Last Updated

10/9/2023

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