Lab Test

Metanephrines, Urine Random

Test Codes

EPIC: LAB7065, Beaker: XMETR, Warde: UMETR

Department

Send Outs

Specimen Collection Criteria

Collect: Random urine in a screw-capped container (preferred) or other sterile collection container. (Minimum: 2.5 mL)

Note: This test is only offered on patients 16 years of age or younger, 24 hour collection is the preferred sample.

Physician Office/Draw Specimen Preparation

Maintain specimen refrigerated (2-8°C or 36-46°F) prior to transport.

Preparation for Courier Transport

Transport: 10.0 mL Random urine, refrigerated (2-8°C or 36-46°F). (Minimum: 5.0 mL)

Rejection Criteria

  • Samples with pH <1
  • Specimens not collected and processed as indicated.

In-Lab Processing

Maintain specimen refrigerated (2-8°C or 36-46°F) prior to transport.

Transport: 10.0 mL Random urine, refrigerated (2-8°C or 36-46°F). (Minimum: 5.0 mL)

Storage

Specimen Stability for Testing:

With preservative:
Room Temperature (20-26°C or 68-78.8°F): 9 days
Refrigerated (2-8°C or 36-46°F): 9 days
Frozen (-20°C/-4°F or below): 30 days

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to Warde Medical Laboratories, Ann Arbor, MI.

Performed

Monday – Friday.
Results available within 2-5 days.

Reference Range

By report.

Test Methodology

High-Performance Liquid Chromatography (HPLC).

Interpretation

Increased metanephrine levels are found in patients with tumors of the adrenal medulla (e.g., pheochromocytoma) or other tumors derived from neural crest cells (e.g., paragangliomas and neuroblastoma).

Alpha-methyldopa (alpha-Aldomet), an anti-hypertensive drug, interferes with this assay.

CPT Codes

83835, 82570.

Contacts

Last Updated

10/9/2023

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