Lab Test

Meconium Drug Panel

Meconium Comprehensive Drug Panel, Meconium Drug Screen, MEC panel

Test Codes

EPIC: LAB479, Beaker: Drug Scr Mec, CHW: LAB479

Department

Send Outs

Instructions

    This panel includes testing for the presence of:

    • THC Metabolite Meconium
    • Morphine Meconium
    • Codeine Meconium
    • Hydrocodone Meconium
    • Hydromorphone Meconium
    • Oxycodone Meconium
    • Oxymorphone Meconium
    • Cocaine Metabolite Meconium
    • Amphetamine Meconium
    • Methamphetamine Meconium
    • Methadone Meconium
    • Fentanyl Meconium

    Specimen Collection Criteria

    Collect:  Meconium in Sterile Screw-Capped Container.

    Preferred Volume to Collect: 5.0 g (about the size of a marble)
    Minimum Volume to Collect:
     1.0 g (approximately 1 teaspoon) 

    • The specimen should be collected into (or transferred from a diaper- diapers not accepted) a clean dry plastic container (no swabs).
    • Transport specimen to the lab immediately.

    Physician Office/Draw Specimen Preparation

    Maintain specimen at room temperature (20-26°C or 68-78.8°F) prior to transport.

    Preparation for Courier Transport

    Transport: 5.0 g meconium, room temperature (20-26°C or 68-78.8°F). (Minimum: 1.0 g)

    Rejection Criteria

    • Yellow stool specimens may be rejected.
    • Specimens not collected and processed as indicated.

    In-Lab Processing

    Maintain specimen at room temperature (20-26°C or 68-78.8°F).

    Transport: 5.0 g meconium, room temperature (20-26°C or 68-78.8°F). (Minimum: 1.0 g)

    Storage

    Specimen Stability for Testing:

    Room Temperature (20-26°C or 68-78.8°F): 24 hours
    Refrigerated (2-8°C or 36-46°F): 72 hours
    Frozen (-20°C/-4°F or below): 1 month

    Specimen Storage in Department Prior to Disposal:

    Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

    Laboratory

    Sent to Corewell Health Reference Laboratory, Grand Rapids, MI.

    Performed

    Monday, Wednesday, Friday.
    Results available in 1-3 days.

    Reference Range

    Cutoff Limits:
    Amphetamines          20.0 ng/g
    Cocaine/Metab.         20.0 ng/g
    Cannabinoids            10.0 ng/g
    Opiates                       20.0 ng/g
            (codeine, morphine, hydrocodone, hydromorphone, oxycodone and oxymorphone)  

    Methadone/EDDP     20.0 ng/g
    Fentanyl                        5.0 ng/g

    Test Methodology

    Liquid Chromatography-Mass Spectrometry (LC-MS)

    Clinical Utility

    Use to detect and document maternal drug use. Useful during approximately the last trimester of a full-term pregnancy.

    For medical purposes only; not valid for forensic use.

    CPT Codes

    80365
    80324
    80349
    80353
    80358
    G0480

    Contacts

    Last Updated

    12/3/2025

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