Lab Test

Isoniazid

Nydrazid

Test Codes

NMS: 2440SP, EPIC: LAB6078, SOFT: XISON

Specimen Collection Criteria

Collect: One plain Red-top tube. (Minimum Whole Blood: 2.0 mL)

Do not use Serum Separator Tubes.

Record the exact time of specimen collection on the tube or in the computer system.
Critical frozen. Send specimen for processing immediately after collection. 

Physician Office/Draw Specimen Preparation

Critical frozen. Let specimen clot 30-60 minutes then centrifuge to separate serum from cells within one hour of collection. Transfer serum to a plastic transport tube and freeze (-20°C/-4°F or below).

Preparation for Courier Transport

Transport: 1.0 mL serum, frozen (-20°C/-4°F or below). (Minimum: 0.4 mL)

Rejection Criteria

  • Severe hemolysis.
  • Serum Separator (SST) tubes.
  • Specimens not collected and processed as indicated.

In-Lab Processing

Critical frozen. Let specimen clot 30-60 minutes then centrifuge to separate serum from cells within one hour of collection. Transfer serum to a plastic transport tube and freeze (-20°C/-4°F or below).

Transport: 1.0 mL serum, frozen (-20°C/-4°F or below). (Minimum: 0.4 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 24 hours
Refrigerated (2-8°C or 36-46°F): 24 hours
Frozen (-20°C/-4°F or below): 1 month

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to ARUP Laboratories, Salt Lake City, UT, forwarded to National Jewish Health, Denver, CO.

Performed

Varies.
Results available in 4-11 days.

Reference Range

By report.

Test Methodology

Quantitative High Performance Liquid Chromatography / Tandem Mass Spectrometry.

Interpretation

By report.

Clinical Utility

Isoniazid acts against actively growing tubercle bacilli. It is indicated in the treatment of pulmonary tuberculosis in which the organisms are susceptible. This assay is used for the therapeutic monitoring and toxicity assessment of isoniazid.

CPT Codes

80375

Contacts

Last Updated

10/10/2020

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This directory currently reflects information only for specimens collected and/or processed at the
Farmington Hills, Grosse Pointe, Royal Oak, and Troy campuses.