Ibuprofen, Serum, Plasma

Motrin, Advil, Nuprin, Ibuprofen Level

Test Codes

EPIC: LAB1232189, Beaker: Ibuprofen, Quest: 5136

Department

Send Outs

Specimen Collection Criteria

Collect (preferred specimen): One plain Red-top tube.
Also acceptable: One Lavender-top (EDTA) tube.

Do not use Serum Separator or Plasma Separator Gel tubes.

Physician Office/Draw Specimen Preparation

Let specimen clot 30-60 minutes then centrifuge to separate serum or plasma from cells. Transfer serum to plastic transport tube and maintain at room temperature (20-26°C or 68-78.8°F) prior to transport.

Preparation for Courier Transport

Transport: 1.0 mL serum or plasma, at room temperature (20-26°C or 68-78.8°F).

Rejection Criteria

• Serum Separator (SST) tubes or Plasma Gel tubes.
• Specimens not collected and processed as indicated.

In-Lab Processing

Let specimen clot 30-60 minutes then centrifuge to separate serum or plasma from cells. Transfer serum to plastic transport tube and maintain at room temperature (20-26°C or 68-78.8°F).

Transport: 1.0 mL serum or plasma, at room temperature (20-26°C or 68-78.8°F). (Minimum: 0.2 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 15 days
Refrigerated (2-8°C or 36-46°F): 15 days
Frozen (-20°C/-4°F or below): 15 days

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to Quest Diagnostics, Wood Dale, IL.

Performed

As needed.
Results available in 8-16 days.

Reference Range

Not detected.

Test Methodology

High Performance Liquid Chromatography / Tandem Mass Spectrometry (LC-MS/MS)

Interpretation

By report.

Clinical Utility

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that also has antipyretic and analgesic activities. This assay is used for the therapeutic monitoring and toxicity assessment of ibuprofen.

CPT Codes

80299

Contacts

Last Updated

12/17/2025