IA-2 Antibody
Insulin Antibodies, Islet-cell Antibodies, GAD65 Antibody, Zinc Transporter 8 Antibody, Diabetes Autoimmune Test Group
Test Codes
EPIC: LAB1232322, Beaker: IA-21, Quest: 37933
Department
Send Outs
Specimen Collection Criteria
Collect (preferred specimen): One plain Red-top tube.
Also acceptable: One Gold-top SST tube.
Physician Office/Draw Specimen Preparation
Let specimen clot 30-60 minutes then centrifuge to separate serum from cells. Transfer serum to plastic transport tube and maintain at room temperature (20-26°C or 68-78.8°F) prior to transport.
Preparation for Courier Transport
Transport: 1.0 mL serum, at room temperature (20-26°C or 68-78.8°F). (Minimum: 0.5 mL)
Rejection Criteria
- Grossly hemolysis.
- Lipemic specimen.
- Specimens not collected and processed as indicated.
In-Lab Processing
Let specimen clot 30-60 minutes then centrifuge to separate serum from cells. Transfer serum to plastic transport tube and maintain at room temperature (20-26°C or 68-78.8°F) prior to transport.
Transport: 1.0 mL serum, at room temperature (20-26°C or 68-78.8°F). (Minimum: 0.5 mL)
Storage
Specimen Stability for Testing:
Room Temperature (20-26°C or 68-78.8°F): 7 days
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): 30 days
Specimen Storage in Department Prior to Disposal:
Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.
Laboratory
Sent to Quest Diagnostics, Wood Dale, IL.
Performed
Tuesday, Thursday, Saturday.
Results are available in 3-5 days.
Reference Range
<5.4 U
Test Methodology
Enzyme Linked Immunosorbent Assay (ELISA)
Clinical Utility
IA-2 Antibody – Type 1 Diabetes Mellitus is characterized by lymphocytic cell infiltration of the beta-cells of pancreatic islets. Measurement of IA-2, GAD-65, ICA-512, and Insulin Antibody is a highly sensitive means to assess risk and predict onset of Type I diabetes.
CPT Codes
86341
Contacts
Send Outs Laboratory – RO
248-551-9045
Name: Send Outs Laboratory – RO
Location:
Phone: 248-551-9045
Last Updated
4/15/2026
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