Hypersensitivity Pneumonitis Screen

Hypersensitivity Pneumonitis I, Hypersensitivity Pneumonitis 2

Test Codes

EPIC: LAB1231934, Beaker: HypSensPneu, Quest: 14978

Department

Send Outs

Instructions

This panel includes:

• Aspergillus fumigatus
• Micropolyspora faeni
• Pigeon Serum
• T. candidus
• T. vulgaris
• S. viridis

Specimen Collection Criteria

Collect (preferred specimen): One Gold-top SST tube.
Also acceptable: One plain Red-top tube.

Physician Office/Draw Specimen Preparation

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells. Transfer serum to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Preparation for Courier Transport

Transport: 2.0 mL serum, refrigerated (2-8°C or 36-46°F). (Minimum: 0.5 mL)

Rejection Criteria

Specimens not collected and processed as indicated.

In-Lab Processing

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells. Transfer serum to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Transport: 2.0 mL serum, refrigerated (2-8°C or 36-46°F). (Minimum: 0.5 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 48 hours
Refrigerated (2-8°C or 36-46°F): 14 days
Frozen (-20°C/-4°F or below): 6 months

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to Quest Diagnostics, Wood Dale, IL.

Performed

Monday – Thursday.
Results available in 3-5 days.

Reference Range

Aspergillus fumigatus    Negative
Micropolyspora faeni     Negative
Pigeon Serum                  Negative
T. candidus                       Negative
T. vulgaris                         Negative
S. viridis                            Negative

Test Methodology

Immunodiffusion

Clinical Utility

Hypersensitivity Pneumonitis Screen – A diagnosis of Hypersensitivity Pneumonitis (an inflammatory lung disease) may be supported by detection of precipitating antibodies to a variety of inhaled antigens associated primarily with molds, bacteria and birds. A positive test does not always indicate active disease and a diagnosis should be supported by historical and clinical evidence, since healthy individuals occasionally might also develop precipitins. A negative test does not preclude a diagnosis of hypersensitivity pneumonitis and should be considered in the context of other laboratory results and clinical findings.

CPT Codes

86331x4, 86606, 86609.

Contacts

Last Updated

11/19/2025