Histoplasma Antibody Panel, CF and ID Serum

Histoplasma capsulatum Antibodies, Histoplasma Antibody, Serum, Histoplasma Antibodies, CF and ID, Histoplasma Mycelial Yeast

Test Codes

EPIC: LAB1232115, Beaker: HISTO AB, Quest: 37094

Department

Send Outs

Specimen Collection Criteria

Collect: One Gold-top SST tube.

Also Acceptable: One plain Red-top tube.

Physician Office/Draw Specimen Preparation

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells. Transfer serum to plastic transport tube and maintain at room temperature (20-26°C or 68-78.8°F) prior to transport.

Preparation for Courier Transport

Transport: 1.0 mL serum, at room temperature (20-26°C or 68-78.8°F). (Minimum: 0.5 mL)

Rejection Criteria

• Gross hemolysis.
• Grossly lipemic.
• Grossly icteric.
• Specimens not collected and processed as indicated.
  

In-Lab Processing

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells. Transfer serum to plastic transport tube and maintain at room temperature (20-26°C or 68-78.8°F).

Transport: 1.0 mL serum, at room temperature (20-26°C or 68-78.8°F). (Minimum: 0.5 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 7 days
Refrigerated (2-8°C or 36-46°F): 14 days
Frozen (-20°C/-4°F or below): 30 days

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to Quest Diagnostics, Wood Dale, IL.

Performed

Information not available.

Reference Range

By report.

Test Methodology

Complement Fixation (CF), Immunodiffusion (ID)

Interpretation

By report.

Clinical Utility

Histoplasmosis, caused by infection by H. capsulatum, is usually asymptomatic or mild. Some patients develop chronic pulmonary histoplasmosis or acute disseminated histoplasmosis that is often life-threatening. Immunodiffusion testing detects antibodies in approximately 70% of patients with histoplasmosis and complement fixation testing detects antibodies in approximately 90% of patients.

CPT Codes

86698 x 3

Contacts

Last Updated

12/11/2025