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High Sensitivity Troponin I Baseline

high sensitivity Troponin I, hsTnI, troponin, troponin panel, cardiac troponin, cTnI, High Sensitivity Troponin & High Sensitivity Troponin I Baseline with Reflex to 2-hour HS Troponin I 

Test Codes

EPIC: LAB1231497-High Sensitivity Troponin I (standalone), EPIC: LAB1231498-High Sensitivity Troponin I Baseline with Reflex to 2-hour HS Troponin I

Department

Chemistry

Specimen Collection Criteria

Taylor, Trenton, Wayne, and Canton:
Collect: One Light Green (Mint)-top Lithium Heparin Plasma Separator Tube (PST). (Minimum Whole Blood: 3.0 mL).

All Other Corewell Health East Locations:
Collect: One Lavendar-top K2EDTA plasma tube. (Minimum Whole Blood: 4.0 mL)
Alternative specimen: One Pearl-top K2EDTA PPT plasma gel separator tube (BD 362788).

Physician Office/Draw Specimen Preparation

Outpatient sites use only LAB1231497 High Sensitivity Troponin I (standalone). Invert tube 8 times for proper mixing of EDTA or Lithium Heparin anticoagulant, then centrifuge immediately to separate plasma from cells. Transfer EDTA plasma to a plastic tube and store plasma aliquot in refrigerator (2-8°C or 36-46°F) (Minimum: 1.0 mL plasma).

Preparation for Courier Transport

  • Centrifuged Pearl-top or Lavender-top, or Light Green (Mint)-top tube, refrigerated (28°C or 36-46°F). (Minimum: 1.0 mL plasma)
  • Labeled aliquot tube, refrigerated (2-8°C or 36-46°F). (Minimum: 1.0 mL plasma) 

Rejection Criteria

  • Pearl-top or lavender top tubes with plasma not separated from cells within eight hours of collection.
  • Specimens collected in inappropriate collection tubes. 
  • Specimens not collected and processed as indicated.
  • Grossly hemolyzed specimens. 

In-Lab Processing

Centrifuge tubes received from inpatient locations to separate plasma from cells. Deliver immediately to the appropriate testing station or add aliquoted labeled plasma sample to the automated line.

Storage

Specimen Stability for Testing:

Pearl-top K2EDTA plasma gel separator tube OR spun-down plasma aliquot
Room Temperature (20-26°C or 68-78.8°F): 24 hours
Refrigerated (2-8°C or 36-46°F): 5 days

Frozen (-20°C/-4°F or below): Unacceptable

Lavender K2EDTA tube
Room Temperature (20-26°C or 68-78.8°F): 8 hours
Refrigerated (2-8°C or 36-46°F): 8 hours
Frozen (-20°C/-4°F or below): Unacceptable

Plasma Aliquot (From Lavender K2EDTA Tube)
Room Temperature (20-26°C or 68-78.8°F): 24 hours
Refrigerated (2-8°C or 36-46°F): 5 days
Frozen (-20°C/-4°F or below): Unacceptable

Light Green (Mint)-top Lithium Heparin Plasma Separator Tube (PST)
Room Temperature (20-26°C or 68-78.8°F): 8 hours
Refrigerated (2-8°C or 36-46°F): 48 hours; spun
Frozen (-20°C/-4°F or below): Unacceptable

Laboratory

Canton Chemistry Laboratory
Dearborn Chemistry Laboratory
Farmington Hills Chemistry Laboratory 
Grosse Pointe Chemistry Laboratory 
Livonia Main Laboratory
Lenox Main Laboratory
Royal Oak Automated Chemistry Laboratory 
Taylor Chemistry Laboratory
Troy Chemistry Laboratory 
Wayne Chemistry Laboratory

Reference Range

< 4 ng/L for single-Troponin rule-out algorithm. 

Female:   ≤ 17 ng/L  (≤ 99th Percentile)
Male:       ≤ 35 ng/L  (≤ 99th Percentile) 

See attached algorithm for significant 2-hour delta Troponin values. 

Test Methodology

Automated Chemiluminescence Immunoassay.

Clinical Utility

> or = 200 ng/L
Delta Troponin > or = 10 ng/L, positive or negative change 

CPT Codes

84484.

Contacts

Last Updated

9/4/2026

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