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Hepatic Function Panel

Liver Function Panel

Test Codes

Antrim #19048, EPIC: LAB5071, HEPFP

Department

Chemistry

Specimen Collection Criteria

FOR EC AND INPATIENT SAMPLE COLLECTION ONLY:

Preferred Sample:  One Light Green Top Plasma Separator Tube (PST)(Minimum Whole Blood: 4.0 mL)

Acceptable Sample:  One Gold Top SST (Minimum Whole Blood:  4.0 mL)

FOR PHYSICIAN OFFICE/OUTREACH SAMPLE COLLECTION:

COLLECT:  One Gold Top SST (Minimum Whole Blood:  4.0 mL) 

Contact Laboratory for acceptability of other tube types.
See Minimum Pediatric Specimen Requirements for Microtainer^® collection.

Physician Office/Draw Specimen Preparation

Let SST specimens clot for 30-60 minutes then immediately centrifuge to separate serum from cells. Refrigerate (2-8°C or 36-46°F) the centrifuged SST tube within two hours of collection. (Minimum: 0.5 mL)

Preparation for Courier Transport

Transport: Centrifuged SST tube, refrigerated (2-8°C or 36-46°F). (Minimum: 0.5 mL)

Rejection Criteria

Moderate to grossly hemolyzed specimens.

Red-top tubes with serum not separated from cells within two hours of collection.

In-Lab Processing

Let SST specimens clot 30-60 minutes. Centrifuge SST tubes or Microtainers^® to separate serum from cells. Deliver immediately to the appropriate testing station.

Storage

Specimen Stability for Testing:

Centrifuged SST Tubes and Microtainers^® with Separator Gel
Room Temperature (20-26°C or 68-78.8°F): 2-4 hours
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): Unacceptable

Red-top Tubes and Microtainers^® without Separator Gel
Room Temperature (20-26°C or 68-78.8°F): 2-4 hours
Refrigerated (2-8°C or 36-46°F): Unacceptable
Frozen (-20°C/-4°F or below): Unacceptable

Serum Specimens (Pour-Overs)
Room Temperature (20-26°C or 68-78.8°F): 2-4 hours
Refrigerated (2-8°C or 36-46°F): 7 days*
Frozen (-20°C/-4°F or below): 7 days

*Total and Direct Bilirubin have a stability of 5 days refrigerated at Grosse Pointe.

Specimen Storage in Department Prior to Disposal:

Refrigerated (2-8°C or 36-46°F): 7 days

Laboratory

Canton Chemistry Laboratory
Dearborn Chemistry Laboratory
Farmington Hills Chemistry Laboratory 
Grosse Pointe Chemistry Laboratory 
Livonia Main Laboratory
Lenox Main Laboratory
Royal Oak Automated Chemistry Laboratory 
Troy Chemistry Laboratory
Taylor Chemistry Laboratory
Trenton Chemistry Laboratory
Wayne Chemistry Laboratory 

Performed

Sunday – Saturday, 24 hours a day. 
Routine results available within 4 hours.

Reference Range

See specific tests for reference ranges.
This panel includes: Albumin, Alkaline Phosphatase, ALT, AST, Bilirubin, Direct, Bilirubin, Total, and Total Protein.

Test Methodology

Spectrophotometry.

Interpretation

See specific analytes for interpretation.
This panel includes: Albumin, Alkaline Phosphatase, ALT, AST, Bilirubin, Direct, Bilirubin, Total, and Total Protein.

Conditions which compromise liver function are associated with increased enzyme levels and bilirubin and decreased albumin. An increased direct bilirubin is seen with intrahepatic or biliary tract obstruction. Total protein may be increased or decreased in liver disease.

Clinical Utility

This panel is used to evaluate or monitor liver function.

CPT Codes

80076

Contacts

Last Updated

5/18/2022