Ganglioside GM-1 Antibodies (IgG, IgM), EIA

Ganglioside-Monosialic Acid Antibodies, GM1 Antibody Panel

Test Codes

EPIC: LAB1231965, Beaker: GANGLIOSIDE, Quest: 37093

Department

Send Outs

Specimen Collection Criteria

Collect (preferred specimen): One Gold-top SST tube. (Minimum: 5.0 mL)
Also acceptable: One plain Red-top tube.

Send specimen for processing immediately after collection.

Physician Office/Draw Specimen Preparation

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells. Transfer serum to a plastic transport tube and refrigerate (2-8°C or 36-46°F) immediately.

Preparation for Courier Transport

Transport: 1.0 mL serum, refrigerated (2-8°C or 36-46°F). (Minimum: 0.2 mL)

Rejection Criteria

• Received room temperature.
• Specimens not collected and processed as indicated.

In-Lab Processing

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells. Transfer serum to a plastic transport tube and refrigerate (2-8°C or 36-46°F) immediately.

Transport: 1.0 mL serum, refrigerated (2-8°C or 36-46°F). (Minimum: 0.2 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 48 hours
Refrigerated (2-8°C or 36-46°F): 14 days
Frozen (-20°C/-4°F or below): 30 days

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to Quest Diagnostics, Wood Dale, IL.

Performed

Monday, Wednesday.
Results available in 4-9 days.

Reference Range

GM-1 Antibody (IgG):  <1:800 Titer
GM-1 Antibody (IgM): <1:800 Titer

IgG, IgM Antibodies to Ganglioside GM1:
Normal                         <1:800
Moderately elevated  <1:800-1:3200
Highly elevated            ≥1:6400

Test Methodology

Immunoassay (IA)

Clinical Utility

Ganglioside GM-1 Antibodies (IgG, IgM), EIA – Ganglioside GM-1 Antibody IgG is associated with the Guillain-Barre syndrome, particularly the acute motor axonal neuropathy variant. Antibody IgM is associated with chronic multifocal motor neuropathy.

CPT Codes

83520 (x2)

Contacts

Last Updated

11/21/2025