Fungal Panel 1, Immunodiffusion

Fungal Antibodies by Immunodiffusion 

Test Codes

EPIC: LAB1231948, Beaker: FUNGAL PANEL, Quest: 7649

Department

Send Outs

Instructions

This assay includes: 

• Aspergillus Antibodies, Immunodiffusion
• Blastomyces Antibody, Immunodiffusion
• Coccidioides Antibody (IgG), Immunodiffusion
• Histoplasma Antibody, Immunodiffusion

Specimen Collection Criteria

Collect: One Gold-top SST tube.
Also acceptable: One plain Red-top tube. 

Physician Office/Draw Specimen Preparation

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells. Transfer serum to a plastic transport tube and maintain at room temperature (20-26°C or 68-78.8°F) prior to transport.

Preparation for Courier Transport

Transport: 2.0 mL serum, maintain at room temperature (20-26°C or 68-78.8°F) prior to transport. (Minimum: 1.0 mL)

Rejection Criteria

• Other body fluids
• Contaminated specimens
• Hemolyzed specimens
• Icteric specimens
• Lipemic specimens
• Specimens not collected and processed as indicated.

In-Lab Processing

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells. Transfer serum to a plastic transport tube and maintain at room temperature (20-26°C or 68-78.8°F) prior to transport.

Transport: 2.0 mL serum, refrigerated (2-8°C or 36-46°F). (Minimum: 1.0 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 7 days
Refrigerated (2-8°C or 36-46°F): 14 days
Frozen (-20°C/-4°F or below): 30 days

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to Quest Diagnostics, Wood Dale, IL.

Performed

Information not provided.

Reference Range

See laboratory report.

Test Methodology

Immunodiffusion (ID).

Clinical Utility

Fungal Panel 1, Immunodiffusion – This immunodiffusion assay is highly specific for histoplasmosis infection but may have low sensitivity in early infection. Two different immunoprecipitin bands may be detected. The M band develops with acute infection, is often present in chronic infection, and may persist for months to years. The H band, which is usually present with the M band, generally suggests a chronic or severe acute infection. The presence of both the H and M bands is considered conclusive for the diagnosis of histoplasmosis.

CPT Codes

86606 (x3), 86612, 86635, 86698.

Contacts

Last Updated

11/19/2025