Lab Test

Fluphenazine Level

Prolixin, Permitil

Test Codes

EPIC: LAB6024, Beaker: XFLUP, ARUP: 99906

Department

Send Outs

Specimen Collection Criteria

Collect (preferred specimen): One plain Red-top tube.
Also acceptable: One Lavender-top EDTA tube.

Do not use Serum Separator Tubes.
Time of Collection: Pre-dose (Trough), at steady state concentration.

Physician Office/Draw Specimen Preparation

Centrifuge to separate serum or plasma from cells within two hours of collection. Transfer serum or plasma to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Preparation for Courier Transport

Transport: 1.0 mL serum or plasma, refrigerated (2-8°C or 36-46°F). (Minimum: 0.5 mL)

Rejection Criteria

  • Serum Separator (SST) tubes.
  • Specimens not collected and processed as indicated.
  • Hemolyzed specimens.

In-Lab Processing

Centrifuge to separate serum or plasma from cells within two hours of collection. Transfer serum or plasma to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Transport: 1.0 mL serum or plasma, refrigerated (2-8°C or 36-46°F). (Minimum: 0.5 mL) 

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 48 hours
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): 30 days

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to ARUP Laboratories, Salt Lake City, UT.

Performed

Monday, Wednesday, Friday.
Results available in 1-8 days.

Reference Range

Therapeutic Range: 1.0-10.0 ng/mL.
Toxic: Greater than 15 ng/mL.

Test Methodology

Quantitative Liquid Chromatography / Tandem Mass Spectrometry.

Interpretation

By report.

Note: The performance characteristics of this test were validated by ARUP Laboratories, Inc. The U.S. Food and Drug Administration (FDA) has not approved this test. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions. ARUP is authorized under Clinical Laboratory Improvement Amendments (CLIA) and by all states to perform high-complexity testing.

Clinical Utility

Fluphenazine is a phenothiazine derivative used in the treatment of psychotic disorders. It is also used to alleviate pain and in childhood development disorders. This assay is used for the therapeutic monitoring and toxicity assessment of fluphenazine.

CPT Codes

80342, (alternate code: G0480).

Contacts

Last Updated

1/9/2024

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