Echovirus Antibodies

Test Codes

EPIC: LAB1231960, Beaker: ECHOVIRUS AB, Quest: 35139

Department

Send Outs

Specimen Collection Criteria

Collect (preferred specimen): One Gold-top SST tube.
Also acceptable: One plain Red-top tube.

Physician Office/Draw Specimen Preparation

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells. Transfer serum to plastic transport tube and maintain at room temperature (20-26°C or 68-78.8°F) prior to transport.

Preparation for Courier Transport

Transport: 2.0 mL serum, room temperature (20-26°C or 68-78.8°F). (Minimum: 1.0 mL)

Rejection Criteria

Specimens not collected and processed as indicated.

In-Lab Processing

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells. Transfer serum to plastic transport tube and maintain at room temperature (20-26°C or 68-78.8°F) prior to transport.

Transport: 2.0 mL serum, room temperature (20-26°C or 68-78.8°F). (Minimum: 1.0 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 7 days
Refrigerated (2-8°C or 36-46°F): 14 days
Frozen (-20°C/-4°F or below): 30 days

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to Quest Diagnostics, Wood Dale, IL.

Performed

Monday – Friday.
Results available in 2-5 days.

Reference Range

Echovirus   4 Ab:  <1:8 titer.
Echovirus   7 Ab:  <1:8 titer.
Echovirus   9 Ab:  <1:8 titer.
Echovirus 11 Ab:  <1:8 titer.
Echovirus 30 Ab:  <1:8 titer.

Test Methodology

Complement Fixation (CF).

Clinical Utility

Echovirus Antibody Panel – The current echovirus panel includes serotypes 4, 7, 9, 11, and 30. The echovirus serotypes used in this panel will vary depending upon current epidemiological data available from inhouse isolations CDC reports. Generally, the serotypes used are those most commonly associated with viral meningitis. Although there is cross-reactivity among the enteroviruses, most healthy people do not have detectable CF titers (>1:8). Therefore, detectable titers, especially those >1:32, should be considered diagnostic. Confirmed serodiagnosis is made by demonstration of a four-fold change in titers between acute and convalescent sera.

CPT Codes

86658 x 5.

Contacts

Last Updated

11/21/2025