Deoxycorticosterone

11-desoxy-17-Hydroxycorticosterone, Cortodoxone, 11-Deoxycorticosterone, 21-Hydroxyprogesterone, DOC, Deoxycortisol Quantitative, Deoxycorticosterone (DOC)

Test Codes

EPIC: LAB1232131, Beaker: Deoxycortico, Quest: 90973

Department

Send Outs

Specimen Collection Criteria

Collect: One plain Red-top tube.

Do not use Serum Separator Tubes (SST).

Physician Office/Draw Specimen Preparation

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells within one hour of collection. Transfer serum to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Preparation for Courier Transport

Transport: 0.5 mL serum, refrigerated (2-8°C or 36-46°F). (Minimum: 0.25 mL)

Rejection Criteria

• Moderate to gross hemolysis.
• Grossly lipemic.
• Grossly icteric.
• Serum separator tube (SST).
• Specimens not collected and processed as indicated.

In-Lab Processing

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells within one hour of collection. Transfer serum to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Transport: 0.5 mL serum, refrigerated (2-8°C or 36-46°F). (Minimum: 0.25 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 7 days
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): 28 days

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to Quest Diagnostics, Wood Dale, IL.

Performed

Sunday, Tuesday.
Results available in 2-8 days.

Reference Range

Adult Male	≤16 ng/dL
Adult Female
Pre-Menopausal Mid Follicular	≤18 ng/dL
Pre-Menopausal Surge	≤23 ng/dL
Pre-Menopausal Mid Luteal	≤19 ng/dL

Pediatric

Age	Male (ng/dL)	Female (ng/dL)
<30 days	Not established	Not established
1-11 months	≤69	≤93
1 year	≤66	≤100
2 years	≤64	≤100
3 years	≤63	≤96
4 years	≤63	≤89
5 years	≤62	≤78
6 years	≤58	≤65
7 years	≤51	≤53
8 years	≤44	≤45
9 years	≤38	≤40
10 years	≤31	≤35
11 years	≤26	≤30
12 years	≤22	≤25
13 years	≤20	≤21
14 years	≤20	≤19
15 years	≤20	≤18
16 years	≤20	≤18
17 years	≤19	≤18

Test Methodology

Chromatography / Mass Spectrometry

Interpretation

By report.

Clinical Utility

Deoxycorticosterone (DOC) is a weak mineralocorticoid derived from 21-hydroxylation of progesterone in the adrenal cortex. DOC is a precursor of corticosterone and aldosterone and, like cortisol, is under the primary control of ACTH.

CPT Codes

82633

Contacts

Last Updated

12/17/2025