D Lactate, Urine
MAYO: DLAU, EPIC: LAB6250, SOFT: XLACU
Please refer to the Specimen Collection Manual for instructions on 24 Hour Urine Collection:
Specimen Collection Criteria
Collect (preferred specimen): 24 hour urine sample with no preservative.
Also acceptable: 2.5 mL of random urine specimen in a screw-capped container (preferred) or other sterile collection cup. (Minimum: 0.65 mL)
- Keep 24 hour urine specimen iced or refrigerated during collection.
- Include start and end dates and times for the collection period on the specimen container.
Urine Preservative Options
6N Hydrochloric Acid
Boric Acid (10g)
50% Acetic Acid
Physician Office/Draw Specimen Preparation
Maintain specimens refrigerated (2-8°C or 36-46°F) prior to transport.
Preparation for Courier Transport
Transport: Entire 24 hour urine collection, or random urine, refrigerated (2-8°C or 36-46°F).
Specimens not collected and processed as indicated.
Measure total volume of 24 hour urine specimen. Record total volume and collection start and end dates and times in the LIS system. Aliquot 2.5 mL from the well-mixed 24 hour urine collection or random urine into a plastic transport tube and freeze. (Minimum: 0.65 mL)
Specimen Stability for Testing:
Room Temperature (20-26°C or 68-78.8°F): 72 hours
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): 1 year
Specimen Storage in Department Prior to Disposal:
Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.
Sent to Mayo Medical Laboratories, Rochester, MN.
Results available in 5-9 days.
D-lactate is a product of bacterial overgrowth in the gastrointestinal tract. It should not be confused with L-lactate which accumulates in some metabolic acidosies.
D-lactate is readily cleared. Urine is the preferred sample.
Elevated levels of D-lactate are often seen in patients with the short-bowel syndrome and following jejunoileal bypass.
This assay is used to investigate D-lactate acidosis. D-lactate acidosis has been described in patients with jejunoileal bypass and short-bowel syndrome.
Send Outs Laboratory – RO
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