Lab Test

Complete Blood Count with Differential (CBCWD)

CBC/DIFF, CBC/D, Peripheral Smear

Test Codes

EPIC: LAB5139 (Inpatient/Outpatient EPIC Users), LAB7909 (Outreach/Non-EPIC Users), Antrim: 27055



Specimen Collection Criteria

Collect (preferred specimen): One 4.0 mL Lavender-top K2EDTA tube. (Minimum: 2.0 mL)
Also acceptable: One Lavender-top K2EDTA Microtainer®. (Minimum: 300 mcL)
See Minimum Pediatric Specimen Requirements for Microtainer® collection.

Note: For known platelet clumper patients, collect one light blue top 3.2% sodium citrate tube (ensure tube is full) and one 4.0 mL lavender-top K2EDTA tube (minimum: 2.0 mL). Label both tubes with the order requested and rubber band the two tubes together. Place a handwritten note with the samples stating “Previous platelet clumper. Deliver both tubes to the hematology lab.”

Physician Office/Draw Specimen Preparation

Maintain specimens refrigerated (2-8°C or 36-46°F) prior to transport. Room temperature (20-26°C or 68-78.8°F) is acceptable for a maximum of 8 hours.

Preparation for Courier Transport

Transport: Whole blood or capillary blood, refrigerated (2-8°C or 36-46°F). (Minimum: 2.0 mL whole blood or 300 mcL capillary blood)

Rejection Criteria

  • Specimens containing clots.
  • Insufficient volume.
  • Frozen specimens.
  • Centrifuged specimens. 


Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 8 hours
Refrigerated (2-8°C or 36-46°F): 72 hours
Frozen (-20°C/-4°F or below): Unacceptable

Specimen Storage in Department Prior to Disposal:

Refrigerated (2-8°C or 36-46°F): 7 days


Canton Laboratory
Dearborn Hematology Laboratory
Farmington Hills Hematology Laboratory
Grosse Pointe Hematology Laboratory
Lenox Laboratory
Livonia Laboratory
Royal Oak Hematology Laboratory
Taylor Hematology Laboratory
Trenton Hematology Laboratory
Troy Hematology Laboratory
Wayne Hematology Laboratory


Sunday – Saturday, 24 hours a day.
Stat results available in 30 minutes; 60 minutes if further verification is necessary.
Routine results available within 90 minutes, unless further verification is necessary.

Reference Range

  WBC (bill/L)3.3-10.73.5-10.1
  RBC (tril/L)3.87-5.084.31-5.48
  Hemoglobin (g/dL)12.1-15.013.5-17.0
  HCT (%)35.4-44.240.1-50.1
  MCV (fL)80-10080-100
  MCH (pg)28-3328-33
  MCHC (g/dL)32-3532-35
  RDW-SD (fL)40-5037-47
  RDW-CV (%)12-1512-15
  Platelet (bill/L)150-400150-400
  Neutrophils (bill/L)1.6-7.21.6-7.2
  Lymphocytes (bill/L)1.1-4.01.1-4.0
  Monocytes (bill/L)0.0-0.80.0-0.9
  Eosinophils (bill/L)0.0-0.50.0-0.4
  Basophils (bill/L)0.0-0.10.0-0.1
  IG (bill/L)0.0-0.030.0-0.04

Please see Pediatric Reference Range.

NOTE: All orders with a WBC < 0.4 bill/L will not have a differential resulted. The order will be changed to a CBCND.

Test Methodology


Clinical Utility

This assay measures the hematologic parameters of the blood. It aids in the evaluation of anemia, leukemia, reaction to inflammation and infections, peripheral blood cell characteristics, state of hydration and dehydration, polycythemia, hemolytic disease of the newborn, and ABO incompatibilities.

CPT Codes



Last Updated


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