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Cocaine Confirmation, Urine

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Test Codes

EPIC: LAB6920, Beaker: CCACF

Department

Toxicology

Specimen Collection Criteria

Collect: 50 mL random urine in a screw-capped container (preferred) or other sterile collection cup with no preservative. (Minimum: 30 mL)

• Refrigerate the specimen immediately after collection.
• Record the exact time of specimen collection on the container or in the computer system.

Physician Office/Draw Specimen Preparation

Maintain specimen refrigerated (2-8°C or 36-46°F) prior to transport.

Preparation for Courier Transport

Transport: 50 mL urine, refrigerated (2-8°C or 36-46°F). (Minimum: 30 mL)

Rejection Criteria

• Specimens not collected and processed as indicated.
• Urine Vacutainer^® tubes. Urine received in a glass or plastic tube with a rubber stopper may contain insufficient sample volume, preclude confirmatory testing, and give rise to contaminants and artifacts. 

In-Lab Processing

Analyze specimen immediately upon receipt in the Laboratory.

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 72 hours
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): 3 months

Specimen Storage in Department Prior to Disposal:

Refrigerated (2-8°C or 36-46°F): 7 days

Laboratory

Toxicology Laboratory, Royal Oak 

Performed

Sunday – Saturday. Results available within 3-5 business days. 

Test Methodology

Gas Liquid Chromatography/Mass Spectrometer (GC/MS).

The confirmation component of this test was developed by Beaumont Health. It has not been cleared or approved by the FDA. The laboratory is regulated under CLIA as qualified to perform high-complexity testing. This test is used for clinical purposes and should not be regarded as investigational or for research.

Interpretation

Drugs identified: Cocaine, Benzoylecgonine, Ecgonine Methyl Ester

Concentrations of drugs and/or metabolite(s) detected in urine have not been correlated to drug levels in the bloodstream or with the degree of impairment. The presence of a drug and/or metabolite(s) in urine is only an indication of previous drug exposure. This assay is a semi-quantitative method for the detection of the primary urinary metabolite of Cocaine, Benzoylecgonine.

Clinical Utility

Cocaine is a frequently abused drug. The drug is administered by nasal insufflation, intravenous injection or in the free base form as smoke inhalation. The urinary elimination of cocaine and its metabolite begins within 20 minutes of its intranasal administration. This assay is used to aid in the diagnosis and treatment of cocaine use or abuse. 

CPT Codes

80353
LOINC: 43985-1, 8191-9, 14315-6

Contacts

Last Updated

10/2/2023