24 Hour Urine: EPIC: LAB541, CLU24, Random Urine: EPIC: LAB5440, CLU
Note: 24 hour and random urine specimens MUST be collected separately. See below for collection criteria.
- Please refer to the Specimen Collection Manual for instructions on 24 Hour or Random Urine Collection:
Specimen Collection Criteria
Collect: 24 hour urine or timed urine specimen with a 24 hour urine container with no preservatives.
Also acceptable: Random urine specimen in a screw-capped container (preferred) or another sterile collection cup. Preservatives are not acceptable for random urine specimens. (Minimum: 20 mL)
- Refer to the table of Urine Preservative Options when multiple tests are requested.
- Keep 24 hour urine specimen iced or refrigerated during collection.
- Include start and end dates and times for the collection period on the specimen container.
Urine Preservative Options
6N Hydrochloric Acid
Boric Acid (10g)
50% Acetic Acid
Physician Office/Draw Specimen Preparation
Maintain specimens refrigerated (2-8°C or 36-46°F) prior to transport.
Preparation for Courier Transport
Transport: Entire 24 hour urine collection, or random urine, refrigerated (2-8°C or 36-46°F).
Specimens not collected and processed as indicated.
Measure total volume of 24 hour urine specimen. Record total volume and collection start and end dates and times in the LIS system. Aliquot a minimum of 10 mL from the well-mixed 24 hour urine collection.
Specimen Stability for Testing:
Room temperature (20-26°C or 68-78.8°F): 4 hours
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): For longer storage.
Specimen Storage in Department Prior to Disposal:
Refrigerated (2-8°C or 36-46°F): 7 days (Royal Oak and Troy store an aliquot for 30 days.)
Dearborn, Chemistry Laboratory
Farmington Hills Chemistry Laboratory
Grosse Pointe Chemistry Laboratory
Royal Oak Automated Chemistry Laboratory
Troy Chemistry Laboratory
Sunday – Saturday.
Results available within 24 hours.
Urine Chloride: 110-250 mmol/24 hours.
Normal ranges for random urines or for collections other than 24 hours have not been established.
Urinary chloride levels less than 10 mmol/L are seen in chloride responsive disorders such as diuretic therapy, GI causes, rapid correction of hypercapnia, carbenicillin administration and reduced dietary intake. Levels greater than 20 mmol/L are seen in chloride unresponsive disorders such as hyperaldosteronism or Cushing's syndrome, exogenous steroid use, Bartter's syndrome, or alkali ingestion.
Urinary chloride measurements aid in the differentiation of causes of metabolic alkalosis and help classify them as chloride responsive or unresponsive.
LOINC: 2079-2, 2078-4
Chemistry Laboratory – DBN
Automated Chemistry Laboratory – RO
Chemistry Laboratory – FH
Chemistry Laboratory – GP
Chemistry Laboratory – TR
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