Lab Test

Anaplasma phagocytophilum Antibodies, (IgG, IgM) with Reflex to Titers

HGA, Human Granulocytic Anaplasmosis, HGE, Human Granulocytic Ehrlichiosis (HGE), HE, Anaplasma Ab IgG, IgM, Human Granulocytic Ehrlichiosis Ab

Test Codes

EPIC: LAB1232292, Beaker: AphagoAb, Quest: 16189

Department

Send Outs

Specimen Collection Criteria

Collect (preferred specimen): One Gold-top SST tube.

Also acceptable: One plain Red-top tube.

Physician Office/Draw Specimen Preparation

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells. Transfer serum to plastic transport tube and maintain at room temperature (20-26°C or 68-78.8°F) prior to transport.

Preparation for Courier Transport

Transport: 1.0 mL serum at room temperature (20-26°C or 68-78.8°F). (Minimum: 0.2 mL)

Rejection Criteria

Specimens not collected and processed as indicated.

In-Lab Processing

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells. Transfer serum to plastic transport tube and maintain at room temperature (20-26°C or 68-78.8°F) prior to transport.

Transport: 1.0 mL serum at room temperature (20-26°C or 68-78.8°F). (Minimum: 0.2 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 7 days
Refrigerated (2-8°C or 36-46°F): 14 days
Frozen (-20°C/-4°F or below): 30 days

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to Quest Diagnostics, Wood Dale, IL.

Performed

Tuesday, Thursday, Saturday.
Results available in 3-4 days. 

Reference Range

A. phagocytophilum Ab (IgG), Screen:  Not detected.
A. phagocytophilum Ab (IgM), Screen:  Not detected.
A. phagocytophilum Ab (IgG), Titer:  
<1:64 titer
A. phagocytophilum 
Ab (IgM), Titer:  <1:20 titer

Test Methodology

Immunofluorescence Assay (IFA)

Clinical Utility

Anaplasma phagocytophilum Antibodies (IgG, IgM) – Anaplasma phagocytophilum is a tick-borne agent that causes an acute febrile illness that often resembles Rocky Mountain spotted fever.

CPT Codes

86666 x 2

Contacts

Last Updated

1/29/2026

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