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Beaumont Laboratory

Chloride

Cl, Serum, EPIC: LAB5132, SOFT: CL

Specimen Collection Criteria

Collect: One Gold-top SST tube. (Minimum Whole Blood: 4.0 mL)

Contact Laboratory for acceptability of other tube types.
See Minimum Pediatric Specimen Requirements for Microtainer® collection.

Physician Office/Drawsite Specimen Preparation

Let SST specimens clot 30-60 minutes then immediately centrifuge to separate serum from cells. Refrigerate (2-8°C or 36-46°F) the centrifuged SST tube within two hours of collection.

Preparation for Courier Transport

Transport: Centrifuged SST tube, refrigerated (2-8°C or 36-46°F). (Min: 0.5 mL)

Rejection Criteria

  • Moderate to grossly hemolyzed specimens.
  • Red-top tubes with serum not separated from cells within two hours of collection.

Storage

Specimen Stability for Testing:

Centrifuged SST Tubes and Microtainers® with Separator Gel
Room Temperature (20-26°C or 68-78.8°F): 2-4 hours
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): Unacceptable

Red-top Tubes and Microtainers® without Separator Gel
Room Temperature (20-26°C or 68-78.8°F): 2-4 hours
Refrigerated (2-8°C or 36-46°F): Unacceptable
Frozen (-20°C/-4°F or below): Unacceptable

Serum Specimens (Pour-Overs)
Room Temperature (20-26°C or 68-78.8°F): 2-4 hours
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): 7 days

Specimen Storage in Department Prior to Disposal:

Refrigerated (2-8°C or 36-46°F): 7 days

Laboratory

Farmington Hills Chemistry Laboratory.
Grosse Pointe Chemistry Laboratory.
Royal Oak Automated Chemistry Laboratory.
Troy Chemistry Laboratory.

Performed

Sunday-Saturday, 24 hours a day.
STAT results available within 1 hour of receipt in the Laboratory.
Routine results available within 4 hours.

Reference Range

Serum: 98-110 mmol/L.

Royal Oak Only
Breast Milk (15 days to 15 months post partum): 6.0-16.0 mmol/L.

Test Methodology

Potentiometric.

Interpretation

  • Increased serum chloride levels are seen in dehydration, acute renal failure, renal tubular acidosis, diabetes insipidus, respiratory alkalosis, salicylate intoxication, and metabolic acidosis associated with prolonged diarrhea and bicarbonate loss.
  • Decreased levels are seen in prolonged vomiting, salt-losing nephritis, Addisonian crisis, aldosteronism, SIADH, respiratory acidosis, metabolic alkalosis, overhydration, burns and congestive heart failure.

Clinical Utility

The quantitation of chloride aids in the diagnosis and treatment of electrolyte and metabolic disorders such as acidosis or alkalosis, dehydration, renal failure and hormone imbalance.

CPT Code

82435.

Test Codes

EPIC: LAB5132, SOFT: CL

Last Updated

12/06/2017

Microtainer® and Vacutainer® are registered trademarks of Becton, Dickinson and Company.
UroVysion® is a registered trademark of Abbott Laboratories. ThinPrep® is a registered trademark of Hologic, Incorporated.

This directory currently reflects information only for specimens collected and/or processed at the Farmington Hills, Grosse Pointe, Royal Oak, and Troy campuses.