Lab Test

Pyrimethamine

Daraprim®

Test Codes

NMS #4045SP, Order as a Miscellaneous Send Out.

Specimen Collection Criteria

Collect (preferred specimen): One plain Red-top tube.
Also acceptable: Two Lavender-top EDTA tubes.

Do not use Serum Separator Tubes.

Physician Office/Draw Specimen Preparation

Centrifuge to separate serum or plasma from cells. Transfer serum or plasma to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Preparation for Courier Transport

Transport: 3.0 mL serum or plasma, refrigerated (2-8°C or 36-46°F). (Minimum: 1.2 mL)

Rejection Criteria

Serum Separator (SST) tubes.

Specimens not collected and processed as indicated.

In-Lab Processing

Centrifuge to separate serum or plasma from cells. Transfer serum or plasma to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Transport: 3.0 mL serum or plasma, refrigerated (2-8°C or 36-46°F). (Minimum: 1.2 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): Undetermined
Refrigerated (2-8°C or 36-46°F): Undetermined
Frozen (-20°C/-4°F or below): Undetermined

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to ARUP Laboratories, Salt Lake City, UT, forwarded to National Medical Services (NMS), Willow Grove, PA.

Performed

Wednesday.
Results available within 4-11 days.

Reference Range

By report.

Test Methodology

Gas Chromatography.

Interpretation

By report.

Clinical Utility

This assay aids in the therapeutic drug monitoring of pyrimethamine an antiparasitic. Daraprim® (pyrimethamine) is indicated for the chemoprophylaxis of malaria in susceptible strains of Plasmodia. Pyrimethamine is also indicated for the treatment of toxoplasmosis.

CPT Codes

80375

Contacts

Last Updated

4/1/2020

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This directory currently reflects information only for specimens collected and/or processed at the
Farmington Hills, Grosse Pointe, Royal Oak, and Troy campuses.