Lab Test

Protein Creatinine Ratio, Urine

Urine Protein/Creatinine Ratio, Protein/Creatinine Ratio, Urine

Test Codes

Antrim #18240, 24 Hour Urine: EPIC: LAB7082, SOFT: PCU24, Random Urine: EPIC: LAB5451, SOFT: UPCR

Instructions

Note: 24 hour and random urine specimens MUST be collected separately. See below for collection criteria.

Please refer to the Specimen Collection Manual for instructions on 24 Hour or Random Urine Collection:

Specimen Collection Criteria

Collect: 24 hour urine or timed urine specimen with a 24 hour urine container with with 10g Boric Acid added prior to the start of collection.
Also acceptable: Random urine specimen in a screw-capped container or another sterile collection cup. (Minimum: 20 mL) 

  • Refer to the table of Urine Preservative Options when multiple tests are requested.
  • Keep 24 hour urine specimen iced or refrigerated during collection.
  • Include start and end dates and times for the collection period on the specimen container.
Urine Preservative Options
No Preservative
6N Hydrochloric Acid
Boric Acid (10g)
Sodium Carbonate
50% Acetic Acid
Preferred
Unacceptable
Acceptable
Unacceptable
Unacceptable

Physician Office/Draw Specimen Preparation

Maintain specimens refrigerated (2-8°C or 36-46°F) prior to transport.

Preparation for Courier Transport

Transport: Random urine, or entire 24 hour urine collection, refrigerated (2-8°C or 36-46°F).

Rejection Criteria

Specimens not collected and processed as indicated. 

In-Lab Processing

Measure total volume of 24 hour urine specimen. Record total volume and collection start and end dates and times in the LIS system. Aliquot a minimum of 10 mL from the well-mixed 24 hour urine collection.


Storage

Specimen Stability for Testing:

Room temperature (20-26°C or 68-78.8°F): 4 hours
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): For longer storage.

Specimen Storage in Department Prior to Disposal:

Refrigerated (2-8°C or 36-46°F): 7 days (Royal Oak and Troy store an aliquot for 30 days.)

Laboratory

Grosse Pointe Chemistry Laboratory
Royal Oak Automated Chemistry Laboratory
Troy Chemistry Laboratory

Performed

Sunday – Saturday.
Results available within 24 hours.

Reference Range

Urine Protein Creatinine Ration: Less than 0.20.

Test Methodology

Spectrophotometry.

Interpretation

This test includes a Urine Protein and a Urine Creatinine assay.

Clinical Utility

This ratio is intended to supplement the investigation of proteinuria and should be used when a rapid determination of urinary protein loss is important. To determine a more accurate assessment of proteinuria, a 24 hour urine collection is recommended.

CPT Codes

82570, 84156.

Contacts

Last Updated

5/5/2020

Microtainer® and Vacutainer® are registered trademarks of Becton, Dickinson and Company.
UroVysion® is a registered trademark of Abbott Laboratories. ThinPrep® is a registered trademark of Hologic, Incorporated.

 

This directory currently reflects information only for specimens collected and/or processed at the
Farmington Hills, Grosse Pointe, Royal Oak, and Troy campuses.