Pancreatic Fluid Chemical Tests
Amylase, Pancreatic Fluid: EPIC: LAB6930, SOFT: AMYPN, CA 19-9, Pancreatic Fluid: EPIC: LAB6957, SOFT: C19PN, CEA, Pancreatic Fluid: EPIC: LAB6961, SOFT: CEAPN,
Note: Royal Oak is the ONLY campus that performs the CA 19-9, Pancreatic Fluid.
- Pancreatic Fluid Chemical testing is available for the following analytes: Amylase, CA 19-9, and CEA. This testing is not a panel and analytes are ordered individually. Please refer to the Lab Test Directory for testing of other analytes and fluid types.
- Testing of fluid analytes or sources not listed in the Lab Test Directory must be approved by a Medical Director. Please contact the Laboratory for more information.
Specimen Collection Criteria
Collect: Body fluid in a sterile collection container or Vacutainer® tube without additive. (Minimum: 1.0 mL)
Send specimen for processing immediately after collection.
Physician Office/Draw Specimen Preparation
Maintain specimen refrigerated (2-8°C or 36-46°F) prior to transport. Room temperature (20-26°C or 68-78.8°F) is acceptable for a maximum of two hours.
Preparation for Courier Transport
Transport: Body fluid in a sterile collection container or Vacutainer® tube, refrigerated (2-8°C or 36-46°F). (Minimum: 1.0 mL)
Specimens grossly contaminated with blood.
Specimens collected in a container or tube with an additive.
Before chemistry testing, centrifuge to remove cellular material.
Specimen Stability for Testing:
Room Temperature (20-26°C or 68-78.8°F): 2 hours
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): Undetermined
Specimen Storage in Department Prior to Disposal:
Refrigerated (2-8°C or 36-46°F): 30 days
Farmington Hills Chemistry Laboratory
Grosse Pointe Chemistry Laboratory
Royal Oak Automated Chemistry Laboratory
Sunday – Saturday, 24 hours a day.
Results available within 4 hours of hours of receipt in the Laboratory.
Reference ranges have not been established.
- Chemiluminescence Immunoassay: CA 19-9, CEA.
- Spectrophotometry: Amylase.
- Pancreatic pseudocysts generally contain significantly elevated amylase (e.g. greater than 250 IU/L), whereas mucinous and serous cysts and adenocarcinoma usually have lower concentrations.
- The higher the CEA concentration the more likely a cyst is a mucinous cyst with increased likelihood of malignancy. CEA greater than 200 ng/mL is very suggestive but not diagnostic of a mucinous cyst. Much lower CEA concentrations are usually seen with non-mucinous cysts. Results should be used in conjunction with clinical information, imaging studies, cytology, and pancreatic cyst tumor markers.
- CA 19-9 concentrations less than or equal to 37 U/mL indicate a low risk for a mucinous cyst, and are more consistent with serous cystadenoma or pseudocyst. However, very low concentrations should be viewed with caution since CA 19-9 is a modified Lewis(a) blood group antigen and may not be produced by Lewis non-secretors.
Testing is used to determine whether a pancreatic cyst is likely to be benign or malignant. However, these results cannot be used in isolation and should be used in conjunction with clinical information, imaging studies, and cytology.
- Khalid A, Brugge W. ACG Practice Guidelines for the Diagnosis and Management of Neoplastic Pancreatic Cysts. Am J Gastroenterology. 2007;102:2339-49.
- Bhutani MS, Gupta V, Guha S et al. Pancreati Cyst Fluid Analysis - A Review. J Gastrointestin Liver Des. 2011;20:175-180.
- Habashi S, Draganov PV. Pancreatic Pseudocyst. World J Gastroenterol. 2009;15:38-47.
- Mayo Medical Laboratory.
82150 (Amylase), 86301 (CA 19-9), 82378 (CEA).
Automated Chemistry Laboratory – RO
Chemistry Laboratory – FH
Chemistry Laboratory – GP
Microtainer® and Vacutainer® are registered trademarks of Becton, Dickinson and Company.
UroVysion® is a registered trademark of Abbott Laboratories. ThinPrep® is a registered trademark of Hologic, Incorporated.
This directory currently reflects information only for specimens collected and/or processed at the
Farmington Hills, Grosse Pointe, Royal Oak, and Troy campuses.