Click here for the Clinical Cytogenomics Laboratory Overview brochure.
Conventional Chromosome Analysis
Conventional Chromosome Analysis identifies structural or numerical chromosome abnormalities characteristic of a variety of malignancies. Identification of these lesions provides important diagnostic and prognostic information.
Conventional Chromosome Analysis is performed on multiple specimen types including:
SNP Array Molecular Karyotyping
SNP Array Molecular Karyotyping can identify clinically significant genomic balance along with copy number neutral loss of heterozygosity (uniparental disomy). Identification of these lesions can provide important diagnostic and prognostic information for:
- Acute Lymphoblastic Leukemia
- Acute Myeloid Leukemia
- Chronic Lymphocytic Leukemia
- Myelodysplastic Syndrome/Myeloproliferative Neoplasm
- Plasma Cell Myeloma
- Renal Cell Carcinoma.
Click here for the Constitutional SNP Array Karyotyping Data Sheet.
Click here for the Oncology SNP Array Karyotyping Data Sheet.
Click here for the Prenatal SNP Array Karyotyping Data Sheet.
Molecular Cytogenetic (FISH) Analysis
Molecular Cytogenetic FISH Analysis is performed on all oncology tissue types including bone marrow, peripheral blood, lymph node, tumor biopsy specimens, and paraffin tissue to identify characteristic chromosome abnormalities important for confirmation of diagnosis, disease classification, staging, prognosis, determining appropriate therapy, and identifying remission or relapse. Applications of FISH Analysis in oncology include:
Disease-specific FISH panels and single FISH assays for:
- ALK Gene Rearrangement in Non-Small Cell Lung Carcinoma
- Alveolar Rhabdomyosarcoma
- Desmoplastic Small Round Cell Tumor
- Ewing’s Sarcoma
- Myxoid Liposarcoma
- Synovial Sarcoma
- TFE3-Renal Cell Carcinoma