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Influenza B Antibodies, IgG and IgM

Test Codes

Mayo: SFLB, EPIC: LAB7604, Beaker:

Instructions

Acute and convalescent samples must be labeled as such; parallel testing is preferred and convalescent samples must be received within 30 days from receipt of the acute samples. Please mark sample plainly as "acute" or "convalescent."

Specimen Collection Criteria

Collect (preferred specimen): One Gold-top SST tube.
Also acceptable: One plain Red-top tube.

Physician Office/Draw Specimen Preparation

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells within two hours of collection. Transfer serum to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Preparation for Courier Transport

Transport: 0.25 mL serum, refrigerated (2-8°C or 36-46°F). (Minimum: 0.15 mL)

Rejection Criteria

• Hemolyzed specimens.
• Lipemic specimens.
• Specimens not collected and processed as indicated.

In-Lab Processing

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells within two hours of collection. Transfer serum to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Transport: 0.25 mL serum, refrigerated (2-8°C or 36-46°F). (Minimum: 0.15 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): unacceptable
Refrigerated (2-8°C or 36-46°F): 14 days
Frozen (-20°C/-4°F or below): 14 days

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to Mayo Clinic Laboratories in Rochester, MN.

Performed

Tuesday, Friday.
Results available in 2-5 days.

Reference Range

By report.

Test Methodology

Immunofluorescence.

Clinical Utility

Influenza B is generally less severe in nature than Influenza A and outbreaks are generally more localized. Serology testing can be used when isolation of the organism by culture is unsuccessful. The presence of IgM class antibody or a fourfold or greater rise in titer in paired (acute and convalescent) specimens indicates recent infection. The presence of IgG class antibody generally indicates past exposure and immunity.

CPT Codes

86710 x2.

Contacts

Last Updated

11/13/2020