Porphyrins, Fractionated, Quantitative, Random Urine

Test Codes

EPIC: LAB1232114, Beaker: Porphyrin RU, Quest: 36592

Department

Send Outs

Instructions

NOTE: includes Coproporphyrin I, Coproporphyrin III, Heptacarboxyporphyrin, Hexacarboxyporphyrin, Pentacarboxyporphyrin, Uroporphyrin I, Uroporphyrin III, Total Porphyrins.

Specimen Collection Criteria

Collect: Urine in sterile screw-cap container.

Physician Office/Draw Specimen Preparation

Protect specimen from light. Maintain specimens refrigerated at (2-8°C or 36-46) prior to transport.

Preparation for Courier Transport

Transport: 2.0 mL of urine protected from light, refrigerated at (2-8°C or 36-46). (Minimum 1.5 mL)

Rejection Criteria

• Not protected from light.
• pH <4.0 (acidified urine).
• Received at room temperature.
• Specimens not collected and processed as indicated.

In-Lab Processing

Protect specimen from light. Maintain specimens refrigerated at (2-8°C or 36-46) prior to transport.

Transport: 2.0 mL of urine protected from light, refrigerated at (2-8°C or 36-46). (Minimum 1.5 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): Unacceptable
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): 30 days

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to Quest Diagnostics, Wood Dale, IL.

Performed

Tuesday – Friday.
Report available in 4-6 days.

Reference Range

Uroporphyrin I	3.6-21.1 mcg/g creat
Uroporphyrin III	≤5.6 mcg/g creat
Heptacarboxyporphyrin	≤3.4 mcg/g creat
Hexacarboxyporphyrin	≤6.3 mcg/g creat
Pentacarboxyporphyrin	≤4.1 mcg/g creat
Coproporphyrin I	6.5-33.2 mcg/g creat
Coproporphyrin III	4.8-88.6 mcg/g creat
Total Porphyrins	27.0-153.6 mcg/g creat

Test Methodology

High Performance Liquid Chromatography (HPLC)

CPT Codes

84120

Contacts

Last Updated

3/6/2026