Lab Test

Opiate Screen, Urine

Opiods, Horse, smack, white lady, scag, M, Junk, Morpho, Opiates Screen, Urine

Test Codes

Antrim #17076, EPIC: LAB7014, OPIT9

Specimen Collection Criteria

Collect: 50 mL random urine in a screw-capped container (preferred) or other sterile collection cup with no preservative. (Minimum: 30 mL)

  • Refrigerate the specimen immediately after collection.
  • Record the exact time of specimen collection on the container or in the computer system.

Physician Office/Draw Specimen Preparation

Maintain specimen refrigerated (2-8°C or 36-46°F) prior to transport.

Preparation for Courier Transport

Transport: 50 mL urine, refrigerated (2-8°C or 36-46°F). (Minimum: 30 mL)

Rejection Criteria

  • Specimens not collected and processed as indicated.
  • Urine Vacutainer® tubes. Urine received in a glass or plastic tube with a rubber stopper may contain insufficient sample volume, preclude confirmatory testing, and give rise to contaminants and artifacts. 

In-Lab Processing

Analyze specimen immediately upon receipt in the Laboratory.


Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 72 hours
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): 3 months

Specimen Storage in Department Prior to Disposal:

Refrigerated (2-8°C or 36-46°F): 7 days


Canton Laboratory
Dearborn Chemistry Laboratory
Farmington Hills Chemistry Laboratory
Grosse Pointe Chemistry Laboratory
Lenox Main Laboratory
Livonia Main Laboratory
Royal Oak Automated Chemistry Laboratory
Royal Oak Toxicology Laboratory
Taylor Chemistry Laboratory
Trenton Chemistry Laboratory
Troy Chemistry Laboratory
Wayne Chemistry Laboratory 

NOTE: Screens are performed at Canton, Dearborn, Farmington Hills, Grosse Pointe, Lenox, Livonia, Royal Oak, Taylor, Trenton, Troy, and Wayne. All confirmations are performed at Royal Oak. 


Sunday – Saturday, 24 hours a day.
STAT results (screen) available within 1 hour of receipt in the Laboratory, confirmation within 36 hours. Routine results available within 48 hours.

Reference Range

Positive cutoff: 300 ng/mL.

Test Methodology

Screen: Enzyme Immunoassay.
Confirmation: Gas Liquid Chromatography/Mass Spectrometer (GC/MS).
Note: Confirmation performed at Royal Oak only.

The confirmation component of this test was developed by Beaumont Health. It has not been cleared or approved by the FDA. The laboratory is regulated under CLIA as qualified to perform high-complexity testing. This test is used for clinical purposes and should not be regarded as investigational or for research.


Codeine, Dihydrocodeine, Hydrocodone, Hydromorphone, and Heroin will produce positive results in addition to Morphine. Oxycodone, Thebaine and other opium alkaloids are reactive but less so than the drugs listed above.

Concentrations of drugs and/or metabolite(s) detected in urine have not been correlated to drug levels in the bloodstream or with the degree of impairment. The presence of a drug and/or metabolite(s) in urine is only an indication of previous drug exposure.

Clinical Utility

Opiates act on several sites of the central nervous system. Their use results in analgesia, drowsiness, mood changes and some mental clouding. This assay is used to aid in the diagnosis and treatment of opiate use or abuse. This assay provides a preliminary analytical result. Positive results are confirmed by chromatographic methods.

CPT Codes

80307, 80361, 80365 (alternate: G0479, G0480).
LOINC: 19295-5, 8219-8, Codeine 16197-6, Morphine 16196-8, Hydrocodone 19483-7, Hydromorphone 18473-9, Oxycodone 19643-6, Oxymorphone 18325-1


Last Updated


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