Lab Test

Fentanyl Screen, Urine

Actiq, Duragesic, Durogesic, Fentanyl and Metabolite, Fentore, Innovar, Instanyl, lonsys, norfentanyl, onsolis, sublimaze

Test Codes

FENT  EPIC: LAB7958

Specimen Collection Criteria

Collect: 50 mL random urine in a screw-capped container (preferred) or other sterile collection cup with no preservative. (Minimum: 15 mL)

  • Refrigerate the specimen immediately after collection.
  • Record the exact time of specimen collection on the container or in the computer system.

Physician Office/Draw Specimen Preparation

Maintain specimen refrigerated (2-8°C or 36-46°F) prior to transport.

Preparation for Courier Transport

Transport: 50 mL urine, refrigerated (2-8°C or 36-46°F). (Minimum: 30 mL)

Rejection Criteria

  • Specimens not collected and processed as indicated.
  • Urine Vacutainer® tubes. Urine received in a glass or plastic tube with a rubber stopper may contain insufficient sample volume, preclude confirmatory testing, and give rise to contaminants and artifacts.

In-Lab Processing

Analyze specimen immediately upon receipt in the Laboratory.

Storage

Room Temperature (20-26°C or 68-78.8°F): 72 hours
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): 3 months

Specimen Storage in Department Prior to Disposal:

Frozen (-20°C/-4°F or below): 1 months

Laboratory

Canton Laboratory
Dearborn Chemistry Laboratory
Farmington Hills Chemistry Laboratory
Grosse Pointe Chemistry Laboratory
Lenox Main Laboratory
Livonia Main Laboratory
Royal Oak Automated Chemistry Laboratory
Royal Oak Toxicology Laboratory
Troy Chemistry Laboratory
Taylor Chemistry Laboratory
Trenton Chemistry Laboratory
Wayne Chemistry Laboratory

NOTE: Screens are performed at Canton, Dearborn, Grosse Pointe, Lenox, Livonia, Royal Oak, Farmington Hills, Taylor, Trenton, Troy, and Wayne. All confirmations are performed at Royal Oak.

Performed

Sunday – Saturday, 24 hours a day.
STAT results (screen) available within 1 hour of receipt in the Laboratory, confirmation within 36 hours. Routine results available within 48 hours.

Reference Range

Negative.

Positive cutoff:  1 ng/mL

Test Methodology

Screen: Immunoassay.
Confirmation: Liquid Chromatography/ Tandem Mass Spectrometer (LC/MS/MS).

NOTE: Confirmation performed at Royal Oak only.

The confirmation component of this test was developed by Beaumont Health. It has not been cleared or approved by the FDA. The laboratory is regulated under CLIA as qualified to perform high-complexity testing. This test is used for clinical purposes and should not be regarded as investigational or for research.

Interpretation

Concentrations of drugs and/or metabolite(s) detected in urine have not been correlated to drug levels in the bloodstream or with the degree of impairment. The presence of a drug and/or metabolite(s) in urine is only an indication of previous drug exposure.

Clinical Utility

Fentanyl is a powerful synthetic opioid analgesic that is similar to morphine but is 80 to 100 times more potent. It is typically used to treat patients with severe pain or to manage pain after surgery. It is also sometimes used to treat patients with chronic pain who are physically tolerant to other opioids. The high potency of fentanyl greatly increases risk of overdose, especially if a person who uses drugs is unaware that a powder or pill contains it.

CPT Codes

80307, 80354 (alternate: G0480)
LOINC: 59673-4, Norfentanyl 66129-8

Contacts

Last Updated

5/19/2022

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UroVysion® is a registered trademark of Abbott Laboratories. ThinPrep® is a registered trademark of Hologic, Incorporated.