Lab Test

Propoxyphene

Darvon®

Test Codes

ARUP #2010464, Order as a Miscellaneous Send Out.

Specimen Collection Criteria

Collect (preferred specimen): One plain Red-top tube.
Also acceptable: One Lavender-top EDTA or Dark Green-top Sodium Heparin tube.

Do not use Serum Separator Tubes.
Time of Collection: Trough, just prior to the next dose.

Physician Office/Draw Specimen Preparation

Centrifuge to separate serum or plasma from cells within two hours of collection. Transfer serum or plasma to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Preparation for Courier Transport

Transport: 1.0 mL serum or plasma, refrigerated (2-8°C or 36-46°F). (Minimum: 0.5 mL)

Rejection Criteria

  • Serum Separator (SST) tubes.
  • Hemolyzed specimens.
  • Specimens not collected and processed as indicated.

In-Lab Processing

Centrifuge to separate serum or plasma from cells within two hours of collection. Transfer serum or plasma to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Transport: 1.0 mL serum or plasma, refrigerated (2-8°C or 36-46°F). (Minimum: 0.5 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 7 days
Refrigerated (2-8°C or 36-46°F): 14 days
Frozen (-20°C/-4°F or below): 3 years

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to ARUP Laboratories, Salt Lake City, UT.

Performed

Monday.
Results available in 3-9 days.

Reference Range

By report.

Test Methodology

Quantitative Liquid Chromatography-Tandem Mass Spectrometry.

Interpretation

Drugs Covered: Propoxyphene and Norpropoxyphene (Propoxyphene Metabolite).
Positive cutoff: 10 ng/mL.

Average serum concentrations on a daily regimen of 65 mg, three times a day, drawn 2 hours after last dosage - Propoxyphene: 420 ng/mL; Norpropoxyphene (25-50% analgesic activity): 1450 ng/mL.

CPT Codes

80367 (alternate code: G0480).

Contacts

Last Updated

4/1/2020

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This directory currently reflects information only for specimens collected and/or processed at the
Farmington Hills, Grosse Pointe, Royal Oak, and Troy campuses.