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Alpha 1 Acid Glycoprotein

Alpha-1-Acid Glycoprotein, Alpha-1 Acid Glycoprotein, NEPH

Test Codes

EPIC: LAB6512, Beaker: XAAG, Mayo: FA1GP

Department

Send Outs

Specimen Collection Criteria

Collect: One plain Red-top tube.
Also acceptable: One Gold-top SST tube.

Physician Office/Draw Specimen Preparation

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells. Transfer serum to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Preparation for Courier Transport

Transport: 1.0 mL serum, refrigerated (2-8°C or 36-46°F). (Minimum: 0.5 mL)

Rejection Criteria

Specimens not collected and processed as indicated.

In-Lab Processing

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells. Transfer serum to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Transport: 1.0 mL serum, refrigerated (2-8°C or 36-46°F). (Minimum: 0.5 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 6 hours
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): 90 days

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to Mayo Clinic Laboratories in Rochester, MN. Forwarded to Quest Diagnostics Nichols Institute, San Juan Capistrano, CA.

Performed

Tuesday, Thursday, Saturday.
Results available in 2–8 days.

Reference Range

By report.

Test Methodology

Fixed Rate Time Nephelometry.

Interpretation

Levels are increased in acute inflammation.

Clinical Utility

Alpha-1-acid glycoprotein is an acute phase reactant whose role is unknown. Early work indicated that the liver is the only site of synthesis, but more recent studies have shown that some tumors are also able to synthesize it. Clinically, alpha-1-acid glycoprotein is used for monitoring acute phase reactions such as inflammatory conditions, rheumatoid arthritis, and malignant neoplasms.

CPT Codes

82985
LOINC:  2685-6

Contacts

Last Updated

12/1/2022